211675-98-8

Basic information

• Product Name: Benzenesulfonamide, N-ethyl-4-nitro-N-phenyl-
• Synonyms: 4-Nitro-benzolsulfonsaeure-(N-aethyl-anilid)
• CAS NO: 211675-98-8
• Molecular Formula: C14H14N2O4S
• Molecular Weight: 306.33700
• Mol File: 211675-98-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-ethyl-4-nitro-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-ethyl-4-nitro-N-phenyl-(211675-98-8)
• EPA Substance Registry System: Benzenesulfonamide, N-ethyl-4-nitro-N-phenyl-(211675-98-8)

Safety Data

• Hazardous Substances Data: 211675-98-8(Hazardous Substances Data)

Upstream product

• 28860-08-4 4-nitrobenzenesulfonyl ethylamine 
• 71-43-2 benzene 
• 91-66-7 N,N-diethylaniline 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 103-69-5 N-ethyl-N-phenylamine 

Downstream Products

• 50497-33-1 4-amino-N-ethyl-N-phenylbenzene sulfonamide 
• 853139-10-3 6-(ethyl-phenyl-sulfamoyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 423136-40-7 6-(ethylphenylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 2-methoxybenzylamide 
• 876303-57-0 2-{[4-(ethyl-phenyl-sulfamoyl)-phenylamino]-methylene}-malonic acid diethyl ester 

Relevant articles and documents

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Sulfamoyl-4-oxoquinoline-3-carboxamides: Novel potentiators of defective ΔF508-cystic fibrosis transmembrane conductance regulator chloride channel gating

The synthesis of a small collection of sulfamoyl-4-oxoquinoline-3- carboxamides is described for use as correctors of defective gating of the ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. Several compounds with submicromolar potency were obtained. N-Ethyl 6-(ethylphenylsulfamoyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (7b) was found to be the most effective sulfonamide corrector of defective ΔF508-CFTR gating.