211676-88-9

Basic information

• Product Name: 5'-O-(4,4'-dimethoxytrityl)-O²-methyluridine
• Synonyms: 5'-O-(4,4'-dimethoxytrityl)-O²-methyluridine
• CAS NO: 211676-88-9
• Molecular Weight: 560.604
• Mol File: 211676-88-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5'-O-(4,4'-dimethoxytrityl)-O²-methyluridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4,4'-dimethoxytrityl)-O²-methyluridine(211676-88-9)
• EPA Substance Registry System: 5'-O-(4,4'-dimethoxytrityl)-O²-methyluridine(211676-88-9)

Safety Data

• Hazardous Substances Data: 211676-88-9(Hazardous Substances Data)

Upstream product

• 58-96-8 uridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 53337-88-5 2-methoxy-1-β-D-ribofuranosyl-pyrimidine-4-one 
• 53337-87-4 (3aR,4R,12R,12aR)-2,2,2-triphenyl-4,5,12,12a-tetrahydro-2H,3aH,8H-4,12-epoxy-2λ5-[1,3,2]dioxaphospholo[4,5-e]pyrimido[2,1-b][1,3]-oxazocin-8-one 
• 22329-20-0 (6R,7R,8S,9R)-7,8-dihydroxy-7,8,9,10-tetrahydro-2H,6H-6,9-epoxypyrimido[2,1-b][1,3]oxazocin-2-one 

Downstream Products

• 872548-08-8 N²-acetyl-5'-O-(4,4'-dimethoxytrityl)isocytidine 
• 872548-10-2 N²-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-{[(triisopropylsilyl)oxy]methyl}isocytidine 
• 872548-05-5 5'-O-(4,4'-dimethoxytrityl)isocytidine 
• 211676-86-7 1-[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-3-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-tetrahydro-furan-2-yl]-2-methoxy-1H-pyrimidin-4-one 

Relevant articles and documents

Synthesis of 2′-O-[(triisopropylsilyl)oxy]methyl (=tom)-protected ribonucleoside phosphoramidites containing various nucleobase analogues

The first results of a study aiming at an efficient preparation of a large variety of 2′-O-[(triisopropylsilyl)oxy]methyl(=tom)-protected ribonucleoside phosphoramidite building blocks containing modified nucleobases are reported. All of the here presente

Synthesis of Uridine Analogues to Probe the Functional Group Requirements of the Hairpin Ribozyme

O4-Methyluridine, O2-methyluridine and 4Huridine phosphoramidites were prepared with 2'-O-silyl protection.The methyl modified pyrimidines were synthesised from uridine via the triazolide (O4-methyl) or 2,5'-cyclo derivative (O2-methyl).An improved synthesis of protected 4-thiouridine was also performed.