211686-27-0Relevant articles and documents
Chemo-enzymatic approach to D-allo-isoleucine
Cambie, Mara,D'Arrigo, Paola,Fasoli, Ezio,Servi, Stefano,Tessaro, Davide,Canevotti, Francesco,Del Corona, Lucio
, p. 3189 - 3196 (2007/10/03)
A mixture of D-alloisoleucine and L-isoleucine derivatives are selectively hydrolysed by enzymatic catalysis (alcalase) allowing the recovery of the D-allo stereoisomer in excellent d.e. and yields. Thus, N-formyl-D-allo- isoleucine benzylester is obtained after enzymatic hydrolysis of the diastereoisomeric mixture or by a crystallisation procedure.
