21198-79-8

Basic information

• Product Name: SELENOSEMICARBAZIDE
• Synonyms: SELENOSEMICARBAZIDE;Selenosemicarbazide,98%
• CAS NO: 21198-79-8
• Molecular Formula: CH₅N₃Se
• Molecular Weight: 138.03
• EINECS: 244-266-8
• Mol File: 21198-79-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 176 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /solid
• Density: g/cm³
• CAS DataBase Reference: SELENOSEMICARBAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: SELENOSEMICARBAZIDE(21198-79-8)
• EPA Substance Registry System: SELENOSEMICARBAZIDE(21198-79-8)

Safety Data

• Hazard Codes: N-T
• Statements: 50/53-33-23/25
• Safety Statements: 61-60-45-28A-20/21
• Hazardous Substances Data: 21198-79-8(Hazardous Substances Data)

Usage

Chemical Properties

OFF-WHITE TO SLIGHTLY GREY CRYSTALLINE POWDER

InChI:InChI=1/CH4N3Se/c2-1(5)4-3/h3H2,(H2,2,4)

Upstream product

• 123-72-8 butyraldehyde 
• 35600-34-1 S-methyl isothiosemicarbazide hydroiodide 
• 21198-80-1 acetone selenosemicarbazone 
• 1314931-57-1 hydrazinyl(methylthio)methanamine 

Downstream Products

• 119247-85-7 acetophenone selenosemicarbazone 
• 110252-52-3 1-(2-hydroxy-phenyl)-ethanone selenosemicarbazone 
• 33144-95-5 benzoyl-selenosemicarbazide 
• 34547-83-6 2-Amino-1,3,4-selenadiazol 
• 34547-87-0 5-phenyl-[1,3,4]selenadiazol-2-ylamine 
• 73753-35-2 2-hydrazino-4,5-diphenyl-1,3-selenazole 
• 20601-83-6 mercury(II) selenide 
• 1450934-29-8 2-(4-methoxybenzoyl)hydrazinecarboselenoamide 
• 1089306-27-3 C₈H₈ClN₃Se 
• 1538-49-4 benzyliden-selenosemicarbazide 
• 17222-70-7 (p-chloro-benzyliden)-selenosemicarbazide 
• 17222-74-1 (p-methoxy-benzyliden)-selenosemicarbazide 

Relevant articles and documents

Co(III) complexes of (1,3-selenazol-2-yl)hydrazones and their sulphur analogues

The first Co(iii) complexes with (1,3-selenazol-2-yl)hydrazones as an unexplored class of ligands were prepared and characterized by NMR spectroscopy and X-ray diffraction analysis. The novel ligands act as NNN tridentate chelators forming octahedral Co(iii) complexes. The impact of structural changes on ligands' periphery as well as that of isosteric replacement of sulphur with selenium on the electrochemical and electronic absorption features of complexes are explored. To support the experimental data, density functional theory (DFT) calculations were also conducted. Theoretical NMR chemical shifts, the relative energies and natural bond orbital (NBO) analysis are calculated within the DFT approach, while the singlet excited state energies and HOMO-LUMO energy gap were calculated with time-dependent density functional theory (TD-DFT). The electrophilic f- and nucleophilic f+ Fukui functions are well adapted to find the electrophile and nucleophile centres in the molecules. Both (1,3-selenazol-2-yl)- and (1,3-thiazol-2-yl)hydrazone Co(iii) complexes showed potent antimicrobial and antioxidant activity. A significant difference among them was a smaller cytotoxicity of selenium compounds.

Macrocyclic glutaminase GLS1 inhibitor or pharmaceutically acceptable salt thereof and preparation method and application thereof

The invention relates to the field of biological medicine, in particular to a series of macrocyclic glutaminase inhibitors, a synthesis method and medical application thereof, and particularly relatesto prevention or treatment of glutaminase related diseases. Meanwhile, the inventor performs a series of in-vitro anti-tumor activity evaluation on the synthesized compounds, and particularly, most of the compounds have good inhibitory activity on cancer cells.