21211-98-3

Basic information

• Product Name: 1-pyridin-2-ylheptan-2-one
• Synonyms: 1-(2-Pyridyl)-2-heptanone; 1-(Pyridin-2-yl)heptan-2-one; 2-heptanone, 1-(2-pyridinyl)-; 2-Heptanone, 1-(2-pyridyl)-
• CAS NO: 21211-98-3
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.2695
• Mol File: 21211-98-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 283.4°C at 760 mmHg
• Flash Point: 132.7°C
• Density: 0.98g/cm³
• Vapor Pressure: 0.00318mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 1-pyridin-2-ylheptan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-pyridin-2-ylheptan-2-one(21211-98-3)
• EPA Substance Registry System: 1-pyridin-2-ylheptan-2-one(21211-98-3)

Safety Data

• Hazardous Substances Data: 21211-98-3(Hazardous Substances Data)

Upstream product

• 49836-16-0 2-(hept-1-yn-1-yl)pyridine 
• 104-94-9 4-methoxy-aniline 
• 109-04-6 2-bromo-pyridine 
• 628-71-7 1-Heptyne 

Relevant articles and documents

Stereo- and regioselective gold(i)-catalyzed hydroamination of 2-(arylethynyl)pyridines with anilines

The gold-catalyzed hydroamination of 2-(arylethynyl)pyridines with anilines affords stereoselectively Z-enamine products with excellent regioselectivity. The reaction proceeds with moderate to excellent yields and accommodates a diverse range of functional groups on alkynes (ether, bromo, trifluoromethyl, acetyl, and carbomethoxy) and anilines (ether, bromo, chloro, and carbethoxy). The stereochemistry of the obtained enamines is complementary to that reported in previous studies. A plausible explanation for the observed selectivity was attained by means of NMR experiments.