212118-11-1Relevant articles and documents
ALDEHYDE CONJUGATES AND USES THEREOF
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Paragraph 0336-0337, (2020/08/20)
The present invention provides compounds and methods of use thereof for the treatment, prevention, and/or reduction of a risk of a disease, disorder, or condition in which aldehyde toxicity is implicated in the pathogenesis, including ocular disorders, skin disorders, conditions associated with injurious effects from blister agents, and autoimmune, inflammatory, neurological and cardiovascular diseases by the use of a primary amine to scavenge toxic aldehydes, such as MDA and HNE.
NOVEL TRAPS IN THE TREATMENT OF MACULAR DEGENERATION
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Page/Page column 30; 31, (2014/08/07)
The present invention is directed to compounds of formula (A): pharmaceutical compositions, and methods of use for treating, reducing a symptom of or reducing the risk of macular degeneration.