212322-77-5 Usage
Description
N-[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine is a complex organic compound that serves as a crucial intermediate in the synthesis of Dabigatran, a nonpeptide direct thrombin inhibitor.
Uses
Used in Pharmaceutical Industry:
N-[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine is used as a key intermediate in the synthesis of Dabigatran (D100090), a nonpeptide direct thrombin inhibitor. N-[[2-[[(4-Cyanophenyl)aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine plays a vital role in the development of anticoagulant medications, which are essential for the prevention and treatment of various thrombotic disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 212322-77-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,2,3,2 and 2 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 212322-77:
(8*2)+(7*1)+(6*2)+(5*3)+(4*2)+(3*2)+(2*7)+(1*7)=85
85 % 10 = 5
So 212322-77-5 is a valid CAS Registry Number.
212322-77-5Relevant articles and documents
Identification, synthesis, and strategy for the reduction of potential impurities observed in dabigatran etexilate mesylate processes
Zheng, Yong-Yong,Shen, Cheng-Wu,Zhu, Mei-Yu,Zhou, Yi-Meng,Li, Jian-Qi
, p. 744 - 750 (2014/07/08)
Synthetic impurities that are present in dabigatran etexilate mesylate were studied, and possible pathways by which these impurities are formed during the manufacturing process were examined. The impurities were monitored by high-performance liquid chromatography, and their structures were determined by mass spectrometry and 1H and 13C NMR. Potential causes for the formation of these impurities are discussed, and strategies to minimize their formation are also described.
