212392-64-8

Basic information

• Product Name: (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester
• Synonyms: (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester
• CAS NO: 212392-64-8
• Molecular Weight: 220.271
• Mol File: 212392-64-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester(212392-64-8)
• EPA Substance Registry System: (S)-1-Pyridin-3-ylmethyl-pyrrolidine-2-carboxylic acid methyl ester(212392-64-8)

Safety Data

• Hazardous Substances Data: 212392-64-8(Hazardous Substances Data)

Upstream product

• 3099-31-8 nicotinyl chloride 
• 2133-40-6 L-proline methyl ester monohydrochloride 

Downstream Products

• 195195-95-0 (S)-2-(hydroxydiphenylmethyl)-1-(3'-pyridylmethyl)pyrrolidine 

Relevant articles and documents

Asymmetric Cyanosilylation of Ketones Catalyzed by Bifunctional Chiral N-Oxide Titanium Complex Catalysts

A new bifunctional catalytic system based on chiral N-oxide titanium complexes has been used for the asymmetric cyanosilylation of ketones. Screening of a variety of chiral N-oxide metal complexes resulted in (1R,2S)-1-(2'-pyridylmethyl)-2-(diphenylhydroxymethyl)pyrrolidine N-oxide titanium complex, which gave O-TMS cyanohydrins in good yields with enantiometric excesses of up to 69 percent. A catalytic cycle based on experimental phenomena and studies was proposed to explain the origin of the asymmetric induction.