212622-34-9

Basic information

• Product Name: 5-chloro-4-phenoxypyridazin-6-one
• Synonyms: 5-chloro-4-phenoxypyridazin-6-one
• CAS NO: 212622-34-9
• Molecular Weight: 222.631
• Mol File: 212622-34-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-chloro-4-phenoxypyridazin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-4-phenoxypyridazin-6-one(212622-34-9)
• EPA Substance Registry System: 5-chloro-4-phenoxypyridazin-6-one(212622-34-9)

Safety Data

• Hazardous Substances Data: 212622-34-9(Hazardous Substances Data)

Upstream product

• 134541-32-5 4,5-Dichloro-2-(1,1-dibromo-2-oxo-propyl)-2H-pyridazin-3-one 
• 108-95-2 phenol 
• 51356-03-7 4,5-dichloro-2-chloromethyl-pyridazin-3(2H)-one 
• 51355-97-6 4,5-dichloro-2-(hydroxymethyl)pyridazin-3(2H)-one 
• 97137-15-0 1-acetoxymethyl-4,5-dichloropyridazin-6-one 
• 932-22-9 4,5-dichloro-2H-pyridazin-3-one 
• 1191453-92-5 4-chloro-5-phenoxy-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one 
• 220663-03-6 4-chloro-2-(chloromethyl)-5-phenoxypyridazin-3-(2H)-one 
• 220663-04-7 1-(acetoxymethyl)-5-chloro-4-phenoxypyridazin-6-one 

Downstream Products

• 1191453-93-6 5-phenoxy-2H-pyridazin-3-one 
• 42190-50-1 4-chloro-5-phenoxy-2-phenyl-3(2H)-pyridazinone 
• 214556-07-7 4-chloro-2-methyl-5-phenoxypyridazin-3(2H)-one 

Relevant articles and documents

PYRIDAZINONE GLUCOKINASE ACTIVATORS

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.

Retro-ene reaction. V. Functionalization of 4,5-dihalopyridazin-6-ones using 1-hydroxymethyl-4,5-dihalopyridazin-6-ones as 1-O, 3-N, 5-O ene- adducts

Functionalization of 1-hydroxymethyl-4,5-dihalopyridazin-6-ones via a retro-ene reaction with some nucleophiles gave regioselectively only 5-halo- 4-substitutedpyridazin-6-ones.

Functionalization of 4,5-Dihalopyridazin-6-ones Using 1-(1,1-Dibromo-2-oxopropyl) Derivatives

Functionalization of 4,5-dihalopyridazin-6-ones using 1-(1,1-dibromo-2-oxopropyl)-4,5-dihalopyridazin-6-ones with some nucleophiles gave regioselectively only 5-halo-4-substituted-pyridazin-6-ones.