212709-00-7

Basic information

• Product Name: 2-HOC₆H₄CH₂OSiMe₃
• Synonyms: 2-HOC₆H₄CH₂OSiMe₃
• CAS NO: 212709-00-7
• Molecular Weight: 196.321
• Mol File: 212709-00-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-HOC₆H₄CH₂OSiMe₃(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HOC₆H₄CH₂OSiMe₃(212709-00-7)
• EPA Substance Registry System: 2-HOC₆H₄CH₂OSiMe₃(212709-00-7)

Safety Data

• Hazardous Substances Data: 212709-00-7(Hazardous Substances Data)

Upstream product

• 90-01-7 salicylic alcohol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 4648-54-8 trimethylsilylazide 
• 1058648-87-5 2-[(methoxymethoxy)methyl]phenol 
• 1058648-91-1 2-[(ethoxymethoxy)methyl]phenol 
• 18544-92-8 1-Trimethylsilanyloxy-2-trimethylsilanyloxymethyl-benzene 
• 90-02-8 salicylaldehyde 

Downstream Products

• 90-01-7 salicylic alcohol 
• 90-02-8 salicylaldehyde 

Relevant articles and documents

Room temperature silylation of alcohols catalyzed by metal organic frameworks

The commercial Al(OH)(BDC) (BDC: 1,4-benzenedicarboxylic acid) metal organic framework (Basolite A100) is a suitable heterogeneous catalyst for the silylation of benzylic and aliphatic alcohols by hexamethyldisilazane in toluene at room temperature. Al(OH

H3PW12O40at the[bmim][FeCl4]: A green catalytic system for alkoxymethylation of alcohols and their one-pot interconversion to acetates and TMS-ethers

12-Tungstophosphoric acid immobilized on [bmim][FeCl4] was found to be an efficient catalyst for chemoselective methoxymethylation and ethxoymethylation of alcohols and also one-pot conversion of MOM- or EOM-ethers to their corresponding acetates and TMS-ethers under thermal conditions and microwave irradiation. These procedures were simple, rapid and the corresponding products were obtained in high yields. The catalyst exhibited remarkable reactivity and was reusable.

Efficient o-trimethylsilylation of alcohols and phenols with trimethylsilyl azide catalyzed by tetrabutylammonium bromide under neat conditions

A very efficient procedure for the trimethylsilylation of a wide variety of alcohols, including primary, allylic, benzylic, secondary, hindered secondary, tertiary, and phenols is reported. The reactions were carried out under neat conditions with trimethylsilyl azide (TMSN3) and, when necessary, in the presence of a catalytic amount (20 mol %) of tetrabutylammonium bromide (TBABr) at 30 or 70 °C. Under catalytic conditions, the yields of the corresponding trimethylsilyl ethers were greater than 91%. This procedure also allows the selective protection of primary and secondary alcohols in the presence of tertiary ones.