213128-01-9

Basic information

• Product Name: diethyl [{4-[(2R)-3-[(tert-butoxycarbonyl)amino]-2-(hydroxymethyl)propyl]phenyl}methyl]phosphonate
• Synonyms: diethyl [{4-[(2R)-3-[(tert-butoxycarbonyl)amino]-2-(hydroxymethyl)propyl]phenyl}methyl]phosphonate
• CAS NO: 213128-01-9
• Molecular Weight: 415.467
• Mol File: 213128-01-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl [{4-[(2R)-3-[(tert-butoxycarbonyl)amino]-2-(hydroxymethyl)propyl]phenyl}methyl]phosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl [{4-[(2R)-3-[(tert-butoxycarbonyl)amino]-2-(hydroxymethyl)propyl]phenyl}methyl]phosphonate(213128-01-9)
• EPA Substance Registry System: diethyl [{4-[(2R)-3-[(tert-butoxycarbonyl)amino]-2-(hydroxymethyl)propyl]phenyl}methyl]phosphonate(213128-01-9)

Safety Data

• Hazardous Substances Data: 213128-01-9(Hazardous Substances Data)

Upstream product

• 213127-76-5 3-acetoxy-2-{4-[(diethoxyphosphoryl)methyl]benzyl}propyl acetate 
• 213127-80-1 (2R)-2-[4-(diethoxyphosphorylmethyl)benzyl]-3-hydroxypropyl acetate 
• 213127-66-3 dimethyl 2-[(4-diethoxyphosphorylmethyl)benzyl]malonate 
• 213127-70-9 diethyl {4-[3-hydroxy-2-(hydroxymethyl)propyl]phenyl}methylphosphonate 
• 108228-81-5 4-(diethoxyphosphorylmethyl)-1-bromomethyl-phenyl 
• 3762-25-2 diethyl 4-methylbenzylphosphonate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 213127-98-1 (2R)-3-[(tert-butoxycarbonyl)amino]-2-{4-[(diethoxyphosphoryl)methyl]benzyl}propyl acetate 

Relevant articles and documents

Enzymatic desymmetrization of prochiral 2-benzyl-1,3-propanediol derivatives: A practical chemoenzymatic synthesis of novel phosphorylated tyrosine analogues

(Phosphonomethyl)phenylalanine (Pmp) and (phosphonodifluoromethyl)phenylalanine (F2Pmp) as well as their β-amino acid congeners were prepared as a protecting variant amenable to the peptide synthesis from readily available 2-benzyl-1,3-propandiols possessing either a diethylphosphonomethyl- or diethylphosphonodifluoromethyl functionality at the para-position via the lipase-catalyzed desymmetrization.