213208-15-2

Basic information

• Product Name: 11-{2-[4-(4-Bromo-butyl)-phenyl]-acetyl}-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one
• CAS NO: 213208-15-2
• Molecular Weight: 464.362
• Mol File: 213208-15-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 11-{2-[4-(4-Bromo-butyl)-phenyl]-acetyl}-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 11-{2-[4-(4-Bromo-butyl)-phenyl]-acetyl}-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one(213208-15-2)
• EPA Substance Registry System: 11-{2-[4-(4-Bromo-butyl)-phenyl]-acetyl}-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one(213208-15-2)

Safety Data

• Hazardous Substances Data: 213208-15-2(Hazardous Substances Data)

Upstream product

• 885-70-1 5H-benzo[e]pyrido[3,2-b][1,4]diazepin-6(11H)-one 

Relevant articles and documents

Synthesis of some substituted dibenzodiazepinones and pyridobenzodiazepinones

Some fluoro- and iodo-derivative of 5-[[4-[(4-diisobutylamino)butyl]-1- phenyl]acetyl]-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepin-11-one and 11-[[4- [(dialkylamino)butyl]-1-phenyl]acetyl]-5,11-dihydro-6H-pyrido[2,3- b][1,4]benzodiazepin-6-ones 6 (Scheme 1) and their analogues were synthesized. The synthesis of dibenzodiazepinones 1 (Scheme 1) is based on the reaction between 1,4-phenylenediamine and substituted benzoic acids. The intermediate pyridobenzodiazepinones 3 (Scheme 1) were prepared by condensation of 2-chloro-3-aminopyridine with methyl anthranilate and its chlorine derivative. The condensation of 4-[(halo)alkyl]phenylacetyl chloride with dibenzodiazepinones and pyridobenzodiazepinones followed by the reaction of mono- or dialkyl- or dialkenylamine provides 6 (Scheme 1).