21324-31-2 Usage
Description
3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol is an organic compound with a unique chemical structure that features a triazolopyrimidinol core and a benzyl group attached to it. 3-BENZYL-3H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol is used as a reactant in the synthesis of 2,9-disubstituted-N6-(arylcarbamoyl)-8-azaadenines. These synthesized compounds serve as new selective A3 adenosine receptor antagonists, which have potential applications in the treatment of various diseases and conditions, such as cancer, neurodegenerative disorders, and inflammatory diseases.
Used in Biochemical and Molecular Modeling Studies:
In addition to its role in the pharmaceutical industry, 3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ol is also utilized in biochemical and molecular modeling studies. These studies aim to understand the interactions between the compound and its target molecules, such as proteins and enzymes, which can provide valuable insights into the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 21324-31-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,3,2 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21324-31:
(7*2)+(6*1)+(5*3)+(4*2)+(3*4)+(2*3)+(1*1)=62
62 % 10 = 2
So 21324-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H9N5O/c17-11-9-10(12-7-13-11)16(15-14-9)6-8-4-2-1-3-5-8/h1-5,7,15H,6H2
21324-31-2Relevant articles and documents
Cytoprotective activities of kinetin purine isosteres
Maková, Barbara,Mik, Václav,Li?ková, Barbora,Gonzalez, Gabriel,Vítek, Dominik,Medvedíková, Martina,Monfort, Beata,Ru?ilová, Veronika,Kadlecová, Alena,Khirsariya, Prashant,Gándara Barreiro, Zoila,Havlí?ek, Libor,Zatloukal, Marek,Soural, Miroslav,Paruch, Kamil,D'Autréaux, Benoit,Hajdúch, Marián,Strnad, Miroslav,Voller, Ji?í
, (2021)
Kinetin (N6-furfuryladenine), a plant growth substance of the cytokinin family, has been shown to modulate aging and various age-related conditions in animal models. Here we report the synthesis of kinetin isosteres with the purine ring replace
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies
Biagi, Giuliana,Bianucci, Anna Maria,Coi, Alessio,Costa, Barbara,Fabbrini, Laura,Giorgi, Irene,Livi, Oreste,Micco, Iolanda,Pacchini, Federica,Santini, Edoardo,Leonardi, Michele,Nofal, Fatena Ahmad,Salerni, Oreste LeRoy,Scartoni, Valerio
, p. 4679 - 4693 (2007/10/03)
A number of N6-(N-arylcarbamoyl)-2-substituted-9-benzyl-8- azaadenines, obtained by a modification of the synthetic scheme used to prepare selective A1 ligands, by only three or two steps, are described. At first we prepared a series
Synthesis of 6-mono- and 5,6-disubstituted 1,2,3-triazolo[4,5-d]pyrimidin- 7-ones
Kislyi,Danilova,Semenov
, p. 1770 - 1776 (2007/10/03)
The reactions of N-substituted 4-amino-3-benzyl-1,2,3-triazole-5- carboxamides with phosphorus oxochloride and dimethylformamide at 80°C or with triethyl orthoacetate and acetic anhydride at 160°C afforded 6-mono- or 5,6-disubstituted 1,2,3-triazolo[4.5-d
