21345-13-1

Basic information

• Product Name: 6-chloro-[1,1'-biphenyl]-3-ol
• Synonyms: 6-chloro-[1,1'-biphenyl]-3-ol
• CAS NO: 21345-13-1
• Molecular Weight: 204.656
• Mol File: 21345-13-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-chloro-[1,1'-biphenyl]-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-[1,1'-biphenyl]-3-ol(21345-13-1)
• EPA Substance Registry System: 6-chloro-[1,1'-biphenyl]-3-ol(21345-13-1)

Safety Data

• Hazardous Substances Data: 21345-13-1(Hazardous Substances Data)

Upstream product

• 580-51-8 [1,1'-biphenyl]-3-ol 
• 202982-72-7 4-chloro-3-iodophenol 
• 98-80-6 phenylboronic acid 
• 73006-78-7 5-chloro[1,1'-biphenyl]-2-amine 
• 2113-47-5 2-acetamidobiphenyl 
• 7148-08-5 N-(5-chloro-[1,1'-biphenyl]-2-yl)acetamide 
• 34883-39-1 2,5-dichlorobiphenyl 

Relevant articles and documents

Catalyst-Controlled Regioselective Chlorination of Phenols and Anilines through a Lewis Basic Selenoether Catalyst

We report a highly efficient ortho-selective electrophilic chlorination of phenols utilizing a Lewis basic selenoether catalyst. The selenoether catalyst resulted in comparable selectivities to our previously reported bis-thiourea ortho-selective catalyst, with a catalyst loading as low as 1%. The new catalytic system also allowed us to extend this chemistry to obtain excellent ortho-selectivities for unprotected anilines. The selectivities of this reaction are up to >20:1 ortho/para, while the innate selectivities for phenols and anilines are approximately 1:4 ortho/para. A series of preliminary studies revealed that the substrates require a hydrogen-bonding moiety for selectivity.

8-Azabicyclo[3.2.1]octane derivatives

The present invention relates to a 8-azabicyclo[3.2.1]octane derivative of Formula I, wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt thereof or solvate thereof. The present invention also relates to a pharmaceutical composition comprising an 8-azabicyclo[3.2.1]octane derivative in admixture with one or more pharmaceutically acceptable auxiliaries and to the use of the 8-azabicyclo[3.2.1]octane derivative in therapy.