213455-52-8

Basic information

• Product Name: 1-Naphthalenecarboxaldehyde, 4-(phenylmethoxy)-
• CAS NO: 213455-52-8
• Molecular Formula: C18H14O2
• Molecular Weight: 262.308
• Mol File: 213455-52-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-Naphthalenecarboxaldehyde, 4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthalenecarboxaldehyde, 4-(phenylmethoxy)-(213455-52-8)
• EPA Substance Registry System: 1-Naphthalenecarboxaldehyde, 4-(phenylmethoxy)-(213455-52-8)

Safety Data

• Hazardous Substances Data: 213455-52-8(Hazardous Substances Data)

Usage

Structure

Substituted naphthalene derivative with a carboxaldehyde group and a phenylmethoxy substituent

Usage

Fragrance ingredient in cosmetic and personal care products, manufacturing of perfumes and fragrances, synthesis of other organic compounds, development of pharmaceuticals and agrochemicals

Biological and pharmacological activities

Potential anti-inflammatory and analgesic properties

Precautions

Potential health and environmental hazards, should be handled and used with caution.

Upstream product

• 100-51-6 benzyl alcohol 
• 607-58-9 1-(phenylmethoxy)naphthalene 
• 68-12-2 N,N-dimethyl-formamide 
• 666829-83-0 benzyl 2-[2-(trimethylsilyl)ethynyl]benzoate 
• 205250-12-0 2-[(trimethylsilanyl)ethynyl]benzoic acid 
• 7770-45-8 4-hydroxy-1-naphthaldehyde 
• 100-39-0 benzyl bromide 
• 23084-88-0 diphenylmethyl vinyl ether 
• 666829-65-8 benzyl 2-ethynylbenzoate 
• 111-34-2 -butyl vinyl ether 
• 100-44-7 benzyl chloride 

Downstream Products

• 87344-63-6 4-benzyloxy-1-naphthoic acid 
• 401468-83-5 2-Phenoxy-3-(4-benzyloxynaphthalen-1-yl)-2-methylpropionic acid ethyl ester 
• 728033-53-2 5-hydroxy-1-benzyloxy-4-naphthalenecarboxaldehyde 

Relevant articles and documents

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Synthesis of Phenalenyl-Fused Pyrylium Cations: Divergent C?H Activation/Annulation Reaction Sequence of Naphthalene Aldehydes with Alkynes

Described herein is the synthesis of stable oxonium-doped polycyclic aromatic hydrocarbons (PAHs) by the rhodium-catalyzed C?H activation/annulations of naphthalene-type aldehydes with internal alkynes. This protocol provides four divergent reaction types, including two unexpected annulations with an oxygen transposition process, which lead to diverse types of phenalenyl-fused pyrylium cations comprising a four-, five-, or six-ring-fused π-conjugated core. The annulations exhibit an exquisite regioselectivity and a high tolerance of sensitive functional groups. These PAHs feature intriguing photophysical properties such as full-color tunable fluorescence emission, high quantum yield, and positively charged core, and can be reduced easily to the phenalenyl radicals.

NOVEL CERCOSPORAMIDE DERIVATIVE

The present invention relates to a novel cercosporamide derivative, a pharmacologically acceptable salt thereof or an ester thereof which has an excellent hypoglycemic effect and is useful as a therapeutic and/or prophylactic agent for diabetes. A cercosporamide derivative having the general formula (I): [wherein X represents an oxygen atom or the like, R1 represents a hydrogen atom or a C1-C6 alkyl group, R2 represents a hydrogen atom, a C1-C6 alkyl group or a C1-C6 halogenated alkyl group, R3 represents a hydrogen atom or a C1-C6 alkyl group, R4 represents a C6-C10 aryl group which may be substituted with one to five group(s) independently selected from Substituent Group a, or the like, n represents 1, 2 or 3, and Substituent Group a represents a halogen atom, a C1-C6 alkyl group, a C1-C6 halogenated alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, a C1-C6 alkoxy group, a C1-C6 halogenated alkoxy group, a C2-C6 alkenyloxy group, a C2-C6 alkynyloxy group and the like], a pharmacologically acceptable salt thereof or an ester thereof.