213476-12-1 Usage
Description
Lansoprazole N-Oxide is an off-white solid that is an impurity of Lansoprazole (L175000) formed during the bulk synthesis of the drug.
Uses
Used in Pharmaceutical Industry:
Lansoprazole N-Oxide is used as an impurity in the bulk synthesis of Lansoprazole (L175000) for the development and manufacturing of pharmaceutical products. It is important to monitor and control the levels of this impurity to ensure the safety, efficacy, and quality of the final drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 213476-12-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,4,7 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 213476-12:
(8*2)+(7*1)+(6*3)+(5*4)+(4*7)+(3*6)+(2*1)+(1*2)=111
111 % 10 = 1
So 213476-12-1 is a valid CAS Registry Number.
213476-12-1Relevant articles and documents
Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drug
Reddy, Ganta Madhusudhan,Mukkanti,Kumar, T. Laxmi,Babu, J. Moses,Reddy, Padi Pratap
, p. 3477 - 3489 (2008/12/23)
Lansoprazole (Prevacid) is an antiulcerative drug used for the treatment of duodenal and gastric ulcers, reflux oesophagitis, and Zollinger-Ellison syndrome. During the bulk synthesis of lansoprazole, we have observed five impurities: lansoprazole N-oxide, lansoprazole sulfone N-oxide, lansoprazole sulfide, lansoprazole sulfone and N-aralkyl lansoprazole. The present work describes the synthesis and characterization of these impurities. Copyright Taylor & Francis Group, LLC.
