213599-20-3

Basic information

• Product Name: 1-(2,2-dibromovinyl)-2-iodobenzene
• Synonyms: 1-(2,2-dibromovinyl)-2-iodobenzene
• CAS NO: 213599-20-3
• Molecular Weight: 387.84
• Mol File: 213599-20-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(2,2-dibromovinyl)-2-iodobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,2-dibromovinyl)-2-iodobenzene(213599-20-3)
• EPA Substance Registry System: 1-(2,2-dibromovinyl)-2-iodobenzene(213599-20-3)

Safety Data

• Hazardous Substances Data: 213599-20-3(Hazardous Substances Data)

Upstream product

• 558-13-4 carbon tetrabromide 
• 26260-02-6 2-iodobenzaldehyde 

Downstream Products

• 766-50-7 (2-iodophenyl)-acetylene 
• 66370-75-0 methyl (2-iodophenyl)acetate 
• 213599-21-4 1-(2-bromoethynyl)-2-iodobenzene 

Relevant articles and documents

Synthesis of Ketones and Esters from Heteroatom-Functionalized Alkenes by Cobalt-Mediated Hydrogen Atom Transfer

Cobalt bis(acetylacetonate) is shown to mediate hydrogen atom transfer to a broad range of functionalized alkenes; in situ oxidation of the resulting alkylradical intermediates, followed by hydrolysis, provides expedient access to ketones and esters. By modification of the alcohol solvent, different alkyl ester products may be obtained. The method is compatible with a number of functional groups including alkenyl halides, sulfides, triflates, and phosphonates and provides a mild and practical alternative to the Tamao-Fleming oxidation of vinylsilanes and the Arndt-Eistert homologation.

Construction of Phenanthrenes and Chrysenes from β-Bromovinylarenes via Aryne Diels-Alder Reaction/Aromatization

A highly efficient transition-metal-free general method for the synthesis of polycyclic aromatic hydrocarbons like phenanthrenes and chrysenes (and tetraphene) from β-bromovinylarenes and arynes has been developed. The reactions proceed via an aryne Diels-Alder (ADA) reaction, followed by a facile aromatization. This is the first report on direct construction of chrysenes (and tetraphene) using the ADA approach. Unlike the literature method which is limited to only 9/10-substituted derivatives, this method gives access to a wide variety of functionalized phenanthrenes.

A sequential metal-catalyzed C-N bond formation in the synthesis of 2-amido-indoles

(Chemical Equation Presented) A sequential metal-catalyzed C-N bond formation employing ortho-haloaryl acetylenic bromides is described. The initial amidation is highly selective for C8P-N bond formation, leading to o-haloaryl-substiluted ynami