213764-92-2 Usage
Description
(S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine is a complex organic compound characterized by its unique molecular structure. It is a chiral molecule, with the "S" configuration indicating the spatial arrangement of its atoms. (S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine is a derivative of pyridine, a basic nitrogen-containing structure, and features an iodine atom at the 5th position, a methoxy group connected to a 2-azetidinyl ring at the 3rd position. Its chemical properties include being a colourless oil, which suggests it may have some solubility in organic solvents.
Uses
Used in Pharmaceutical Industry:
(S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine is used as a pharmaceutical compound for its potential therapeutic applications. Given its structural complexity and the presence of bioactive functional groups, it may interact with various biological targets, such as receptors or enzymes, which could make it a candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, (S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine can serve as a starting material or intermediate for the synthesis of more complex molecules with specific biological activities. Its unique structure may be exploited to create novel compounds with improved properties or selectivity towards certain biological targets.
Used in Neuropharmacology:
(S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine is used as a potent and subtype-selective agonist for AChR α4β2 and AChR α6β2. These nicotinic acetylcholine receptors are involved in various cognitive functions and have been implicated in neurological disorders. The compound's ability to selectively activate these receptor subtypes could make it a valuable tool in studying their roles in the nervous system and potentially in developing treatments for related conditions.
Please note that the provided materials do not specify the uses of (S)-5-Iodo-3-[(2-azetidinyl)-methoxy]pyridine directly. The uses listed above are inferred based on the compound's structural features and the general applications of similar compounds in the fields of pharmaceuticals, chemical research, and neuropharmacology.
Biological Activity
A highly potent and subtype-selective agonist for the α 4 β 2 and α 6 β 2 nicotinic acetylcholine receptors. Activates α -CTx-MII-sensitive and -insensitive components of [ 3 H]dopamine release from rat striatal synaptosomes, corresponding to α 6 β 2 and α 4 β 2 (EC 50 values are 12.7 and ~35 nM respectively). ~5000- , 25000- and 140000-fold selective over α 3 β 4, α 7 and muscle nAChR receptors respectively.
Check Digit Verification of cas no
The CAS Registry Mumber 213764-92-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,3,7,6 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 213764-92:
(8*2)+(7*1)+(6*3)+(5*7)+(4*6)+(3*4)+(2*9)+(1*2)=132
132 % 10 = 2
So 213764-92-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H11IN2O.2ClH/c10-7-3-9(5-11-4-7)13-6-8-1-2-12-8;;/h3-5,8,12H,1-2,6H2;2*1H/t8-;;/m0../s1
