213823-33-7Relevant articles and documents
Positioning of functionalities in a heteroduplex major groove: Synthesis of 7-deaza-2-amino-2'-deoxyadenosines
Balow, Guity,Brugger, John,Lesnik, Elena,Acevedo, Oscar L.
, p. 941 - 944 (2007/10/03)
We have synthesized the 7-iodo-, 7-cyano- and 7-propynyl-7-deaza-2- amino-2'-deoxyadenosines and incorporated each into several oligonucleotide (ODN) sequences. These oligonucleotides exhibit enhanced binding affinities to RNA complements relative to unmo