213834-81-2

Basic information

• Product Name: 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one
• Synonyms: 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one
• CAS NO: 213834-81-2
• Molecular Weight: 358.35
• Mol File: 213834-81-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one(213834-81-2)
• EPA Substance Registry System: 6-benzoyl-5,7-dihydroxy-4-phenyl-2H-chromen-2-one(213834-81-2)

Safety Data

• Hazardous Substances Data: 213834-81-2(Hazardous Substances Data)

Upstream product

• 7758-73-8 5,7-dihydroxy-4-phenyl-2H-1-benzopyran-2-one 
• 98-88-4 benzoyl chloride 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 108-73-6 3,5-dihydroxyphenol 
• 3555-86-0 2-benzoylphloroglucinol 

Relevant articles and documents

6-Acyl-4-aryl/alkyl-5,7-dihydroxycoumarins as anti-inflammatory agents

A series of coumarin derivatives were synthesized in two steps from phloroglucinol. The anti-inflammatory activities of these derivatives were evaluated by means of inhibiting NO production in LPS-induced RAW 264.7 cells. Derivatives 3, 8, 10, 11, and 13 exhibited low micromolar levels of anti-inflammatory activities, and these derivatives also protected DNA against hydroxyl radical attack. Coumarin derivative 8 was the most potent derivative among those tested herein against NO production in LPS-induced RAW 264.7 cells with an IC50 value of 7.6 μM, and it effectively reduced the hydroxyl radical production by 50% at 100 μM in the electron spin resonance study.

Minor coumarins from Calophyllum teysmannii var. inophylloide and synthesis of cytotoxic calanone derivatives

A chemotaxonomic survey for biologically active compounds from Malaysian Calophyllum species led to the finding of the four new benzoylcoumarins 1a, 2, 3, and 4a (including the unusual prenylated 6-benzoylcoumarin 1a, two uncommon coumarins 5 and 6a with