21386-65-2Relevant articles and documents
Stereospecific catalytic labelling of amino-acids and mandelic acid with isotopic hydrogen.
Calf,Garnett,Halpern,Turnbull
, p. 502 - 504 (1966)
-
Solution-Phase Raman Studies of Alanyl Dipeptides and Various Isotopomers: A Reevaluation of the Amide III Vibrational Assignment
Oboodi, M. Reza,Alva, Carlos,Diem, Max
, p. 501 - 505 (1984)
Solution-phase Raman spectra of L-alanyl-L-alanine and five nitrogen and/or α-deuterated isotopomers are reported.Detailed vibrational assignments on this set of spectra have led to a somewhat different interpretation of the amide III vibrational region, as compared to literature assignments.The differences result from the fact that, in these deuterated samples, the nature of certain vibrations, and their interactions with other vibrations of similar energies, may be investigated with very high sensitivity.A discussion of the observed interaction of the amide III vibration and the methine deformation is presented, leading to an explanation for the geometric sensitivity of the band commonly referred to as the "amide III" mode.
Enantiospecific C-H Activation Using Ruthenium Nanocatalysts
Taglang, Céline,Martínez-Prieto, Luis Miguel,Del Rosal, Iker,Maron, Laurent,Poteau, Romuald,Philippot, Karine,Chaudret, Bruno,Perato, Serge,Sam Lone, Ana?s,Puente, Céline,Dugave, Christophe,Rousseau, Bernard,Pieters, Grégory
supporting information, p. 10474 - 10477 (2015/09/02)
The activation of C-H bonds has revolutionized modern synthetic chemistry. However, no general strategy for enantiospecific C-H activation has been developed to date. We herein report an enantiospecific C-H activation reaction followed by deuterium incorporation at stereogenic centers. Mechanistic studies suggest that the selectivity for the α-position of the directing heteroatom results from a four-membered dimetallacycle as the key intermediate. This work paves the way to novel molecular chemistry on nanoparticles.
Enantioselective synthesis of α-deuterium labelled chiral α-amino acids via dynamic kinetic resolution of racemic azlactones
Oh, Joong-Suk,Kim, Kyung Il,Song, Choong Eui
supporting information; experimental part, p. 7983 - 7985 (2012/01/04)
Catalytic dynamic kinetic resolution (DKR) of racemic azlactones with EtOD using squaramide-based dimeric cinchona alkaloid organocatalysts is shown to be a highly effective strategy for the preparation of enantiomerically pure α-deuterated chiral α-amino