21411-21-2 Usage
Description
3,4-Dihydro-7-hydroxy-1-[(3-hydroxy-4-Methoxyphenyl)Methyl]-6-Methoxy-2-MethylisoquinoliniuM Iodide is a complex organic compound characterized by its pale yellow solid appearance. It is a dehydro iminium salt derivative of Reticuline (R188500) and serves as a crucial precursor in the synthesis of Multifloramine.
Uses
Used in Pharmaceutical Industry:
3,4-Dihydro-7-hydroxy-1-[(3-hydroxy-4-Methoxyphenyl)Methyl]-6-Methoxy-2-MethylisoquinoliniuM Iodide is used as a key intermediate in the synthesis of Multifloramine, a compound with potential therapeutic applications. Its role in the production of Multifloramine makes it valuable for research and development in the pharmaceutical sector.
Used in Chemical Synthesis:
As a dehydro iminium salt derivative of Reticuline, this compound is utilized in various chemical synthesis processes. Its unique structure allows it to participate in a range of reactions, making it a versatile component in organic chemistry.
Used in Research and Development:
Due to its involvement in the synthesis of Multifloramine, 3,4-Dihydro-7-hydroxy-1-[(3-hydroxy-4-Methoxyphenyl)Methyl]-6-Methoxy-2-MethylisoquinoliniuM Iodide is also used in research and development settings. Scientists and researchers explore its properties and potential applications, furthering the understanding of its role in chemical and pharmaceutical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 21411-21-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,1 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21411-21:
(7*2)+(6*1)+(5*4)+(4*1)+(3*1)+(2*2)+(1*1)=52
52 % 10 = 2
So 21411-21-2 is a valid CAS Registry Number.
21411-21-2Relevant articles and documents
PURIFICATION AND PROPERTIES OF 1,2-DEHYDRORETICULINE REDUCTASE FROM PAPAVER SOMNIFERUM SEEDLINGS
De-Eknamkul, Wanchai,Zenk, Meinhart H.
, p. 813 - 822 (2007/10/02)
1,2-Dehydroreticuline reductase, the NADPH-dependent enzyme which reduces stereospecifically 1,2-dehydroreticuline to (R)-reticuline has been discovered in seedlings of the opium poppy (Papaver somniferum).The enzyme has been purified to apparent electrophoretic homogeneity by ammonium sulphate precipitation and five subsequent column chromatography steps.The isolated enzyme is a single polypeptide with Mr 30000 and has a pH optimum at 8.5 and a temperature optimum at 30 deg.The apparent Km values for 1,2-dehydroreticuline and NADPH are 10 and 7 μM, respectively.The enzyme mediates the transfer of the pro-S-hydride of NADPH to C-1 of 1,2-dehydroreticuline with high substrate specificity; neither 1,2-dehydrynorreticuline nor 1,2-dehydrococlaurine are utilized by the enzyme.The enzyme activity is inhibited by (S)- and (R)-reticuline with I50 values of 0.05 and 0.10 mM, respectively.The reductase is a cytosolic enzyme and present only in morphinan alkaloid-containing plants.This highly species-, substrate- and stereospecific enzyme catalyses the provision of (R)-reticuline for the formation of morphinan alkaloids that possess also (R)-configuration at that chiral centre. Key Word Index - Papaver somniferum; Papaveraceae; 1,2-dehydroreticuline; (R)-reticuline; 1,2-dehydroreticuline reductase; purification; characterization; alkaloid biosynthesis; morphinans.