214193-12-1

Basic information

• Product Name: (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
• Synonyms: (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
• CAS NO: 214193-12-1
• Molecular Formula: C₆H₉NO₂
• Molecular Weight: 127
• Mol File: 214193-12-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID(214193-12-1)
• EPA Substance Registry System: (1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID(214193-12-1)

Safety Data

• Hazardous Substances Data: 214193-12-1(Hazardous Substances Data)

Usage

Description

(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid is a chiral chemical compound with a unique fused bicyclic structure that contains a nitrogen atom. Its three stereocenters, indicated by the R and S notations, determine its spatial arrangement in three-dimensional space. As a carboxylic acid, it has a functional group composed of a carboxyl group (–COOH), which is important for its reactivity and ability to form salts and esters.

Uses

Used in Pharmaceutical Industry:
(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid is used as a building block for the synthesis of pharmaceutical compounds due to its unique structure and potential for modulating biological activity.
Used in Organic Synthesis:
(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid is used as an intermediate in the synthesis of various organic compounds, taking advantage of its reactivity and ability to form salts and esters.
Used in Stereochemical Research:
(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxylic acid is used as a model compound for studying stereochemical effects in chemical reactions and biological processes, given its three-dimensional shape and chiral nature.

Upstream product

• 214193-10-9 2-aza-bicyclo[3.1.0]hexane-2,3-dicarboxylic acid 2-tert-butyl ester 3-ethyl ester 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 194594-23-5 5-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 
• 194594-24-6 (2S)-1-t-butyl 2-ethyl 5-methoxypyrrolidine-1,2-dicarboxylate 
• 178172-26-4 (5S)-4,5-dihydro-1H-pyrrol-1,5-dicarboxylic acid [1-(1,1-dimethylethyl)] 5-ethyl ester 
• 197142-34-0 (1R,3S,5R)-2-(tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 

Relevant articles and documents

MASP INHIBITORY COMPOUNDS AND USES THEREOF

The present invention relates to novel Mannose-binding lectin (MBL)-associated serine protease (MASP) inhibitory compounds, as well as analogues and derivatives thereof, to processes for the preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of renal and cardiovascular disorders and of ischemia reperfusion injuries.