21438-66-4 Usage
Description
GLY-PHE BETA-NAPHTHYLAMIDE, also known as Gly-Phe-β-naphthylamide, is an N-(2-naphthyl)carboxamide compound that is formed through the formal condensation of the carboxy group of glycyl-L-phenylalanine with the amino group of 2-naphthylamine. It is a molecule of interest due to its ability to accumulate inside lysosomes, leading to their destruction.
Uses
Used in Lysosomal Research:
GLY-PHE BETA-NAPHTHYLAMIDE is used as a lysosomal disruptor for studying the effects of lysosomal destruction on cellular processes. Its ability to accumulate inside lysosomes and cause their destruction makes it a valuable tool in understanding the role of lysosomes in various cellular functions and diseases.
Used in Apoptosis Studies:
GLY-PHE BETA-NAPHTHYLAMIDE is used as an inhibitor of caspase-8 activation for investigating the role of caspase-8 in apoptosis. Studies have reported that it significantly inhibits the activation of caspase-8, providing insights into the mechanisms of programmed cell death and potential therapeutic targets for related diseases.
Used in Enzyme Research:
GLY-PHE BETA-NAPHTHYLAMIDE is used as a substrate for studying the activity of recombinant cathepsin C, a lysosomal protease. By using this compound, researchers can gain a better understanding of the enzyme's function and its role in various biological processes.
Check Digit Verification of cas no
The CAS Registry Mumber 21438-66-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,3 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21438-66:
(7*2)+(6*1)+(5*4)+(4*3)+(3*8)+(2*6)+(1*6)=94
94 % 10 = 4
So 21438-66-4 is a valid CAS Registry Number.
InChI:InChI=1/C21H21N3O2/c22-14-20(25)24-19(12-15-6-2-1-3-7-15)21(26)23-18-11-10-16-8-4-5-9-17(16)13-18/h1-11,13,19H,12,14,22H2,(H,23,26)(H,24,25)
