214554-37-7

Basic information

• Product Name: 3-(3-Fluoro-4-hydroxymethyl-phenyl)-propionic acid ethyl ester
• Synonyms: 3-(3-Fluoro-4-hydroxymethyl-phenyl)-propionic acid ethyl ester
• CAS NO: 214554-37-7
• Molecular Weight: 226.248
• Mol File: 214554-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-Fluoro-4-hydroxymethyl-phenyl)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-Fluoro-4-hydroxymethyl-phenyl)-propionic acid ethyl ester(214554-37-7)
• EPA Substance Registry System: 3-(3-Fluoro-4-hydroxymethyl-phenyl)-propionic acid ethyl ester(214554-37-7)

Safety Data

• Hazardous Substances Data: 214554-37-7(Hazardous Substances Data)

Upstream product

• 214554-23-1 4-((E)-2-Ethoxycarbonyl-vinyl)-2-fluoro-benzoic acid benzyl ester 
• 214554-20-8 2-Fluoro-4-hydroxymethyl-benzoic acid benzyl ester 
• 214554-39-9 2-Fluoro-4-formyl-benzoic acid benzyl ester 
• 214554-18-4 2-fluoro-4-(hydroxymethyl)benzoic acid 
• 5292-47-7 1,4-dimethyl 2-fluorobenzene-1,4-dicarboxylate 
• 214554-25-3 4-(2-Ethoxycarbonyl-ethyl)-2-fluoro-benzoic acid 

Relevant articles and documents

Fluorinated linkers for monitoring solid-phase synthesis using gel- phase 19F NMR spectroscopy

Three fluorinated linkers which are analogues of linkers commonly used in solid-phase peptide synthesis have been prepared. Using 19F NMR spectroscopy, the fluorine atom of the linker allowed monitoring of several transformations in the solid-phase synthesis of a peptoid having a coumarin moiety. Especially, attachment of the linker to the solid phase, coupling of the first building block to the linker and cleavage of the product were efficiently monitored and optimised.