21462-56-6 Usage
Description
Thyroxine glucuronide, also known as Thyroxine 4-O-β-D-Glucuronide, is a major metabolite and glucuronide conjugate of Thyroxine (T425600). It is formed through the glucuronidation of the phenyl hydroxyl group. Thyroxine glucuronide is an off-white to pale yellow solid and plays a significant role in the metabolism and regulation of thyroid hormones in the body.
Uses
Used in Pharmaceutical Industry:
Thyroxine glucuronide is used as a pharmaceutical compound for the development of medications targeting thyroid hormone regulation. Its role in the metabolism of thyroid hormones makes it a potential candidate for the treatment of various thyroid-related disorders, such as hypothyroidism and hyperthyroidism.
Used in Diagnostic Applications:
Thyroxine glucuronide can be utilized as a biomarker in the diagnosis of thyroid dysfunction. Its presence and levels in the body can provide valuable information about the status of an individual's thyroid function, aiding in the detection and monitoring of thyroid-related conditions.
Used in Research and Development:
In the field of research, thyroxine glucuronide serves as an important compound for studying the mechanisms of thyroid hormone metabolism and regulation. It can be used in experimental setups to investigate the effects of various factors on thyroid hormone homeostasis and to develop new therapeutic strategies for thyroid disorders.
Used in Drug Delivery Systems:
Similar to gallotannin, thyroxine glucuronide can be incorporated into drug delivery systems to improve the bioavailability and therapeutic outcomes of thyroid hormone-related medications. By employing various organic and metallic nanoparticles as carriers, the delivery, efficacy, and targeting of thyroxine glucuronide-based drugs can be enhanced, potentially leading to more effective treatments for thyroid-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 21462-56-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,4,6 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 21462-56:
(7*2)+(6*1)+(5*4)+(4*6)+(3*2)+(2*5)+(1*6)=86
86 % 10 = 6
So 21462-56-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H19I4NO10/c22-8-1-6(3-12(26)19(30)31)2-9(23)16(8)34-7-4-10(24)17(11(25)5-7)35-21-15(29)13(27)14(28)18(36-21)20(32)33/h1-2,4-5,12-15,18,21,27-29H,3,26H2,(H,30,31)(H,32,33)/t12-,13-,14-,15+,18-,21?/m0/s1