214752-00-8Relevant articles and documents
Reactions of n-arylsulfonyl-2,3-cis- and n-arylsulfonyl-2,3-frans-3-alkyl-2-vinylaziridines with organocopper reagents: importance of 2,3-cis-stereochemistry in controlling regio- and stereoselectivity
Toda, Ayako,Aoyama, Hiroshi,Mimura, Norio,Ohno, Hiroaki,Fujii, Nobutaka,Ibuka, Toshiro
, p. 7053 - 7061 (2007/10/03)
Although reactions of 2,3-trans-N-arylsulfonyl-3-alkyl-2-alkenylaziridines with organocopper reagents give a mixture of two or three products, the corresponding 2,3-cis-isomers provide a highly efficient route to synthetically important nonracemic CE)-allylamines. It is also found that the reaction proceeds via the well-known anti-SN2′ pathway.