2148-57-4 Usage
Description
4,7-Dichloroquinazoline is an organic compound characterized by the presence of two chlorine atoms at the 4th and 7th positions of the quinazoline ring. It is a versatile building block in the field of organic synthesis and has demonstrated potential as a therapeutic agent.
Uses
Used in Pharmaceutical Industry:
4,7-Dichloroquinazoline is used as a building block for the synthesis of aroylquinazolines via aroylation with aryl aldehydes. This application is significant due to the diverse range of biological activities exhibited by quinazoline derivatives, including anti-cancer, anti-bacterial, and anti-viral properties.
Used in Antiviral Applications:
4,7-Dichloroquinazoline has been identified as a dengue virus entry inhibitor. It serves as a potential therapeutic agent for the treatment of dengue fever, a mosquito-borne viral illness that poses a significant global health threat. The compound's ability to inhibit the entry of the dengue virus into host cells makes it a valuable asset in the development of antiviral drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 2148-57-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,4 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2148-57:
(6*2)+(5*1)+(4*4)+(3*8)+(2*5)+(1*7)=74
74 % 10 = 4
So 2148-57-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H4Cl2N2/c9-5-1-2-6-7(3-5)11-4-12-8(6)10/h1-4H
