21486-59-9

Basic information

• Product Name: α-Acetyl-β-amino-2,6-dichlorocinnamonitrile
• Synonyms: α-Acetyl-β-amino-2,6-dichlorocinnamonitrile
• CAS NO: 21486-59-9
• Molecular Weight: 255.103
• Mol File: 21486-59-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-Acetyl-β-amino-2,6-dichlorocinnamonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α-Acetyl-β-amino-2,6-dichlorocinnamonitrile(21486-59-9)
• EPA Substance Registry System: α-Acetyl-β-amino-2,6-dichlorocinnamonitrile(21486-59-9)

Safety Data

• Hazardous Substances Data: 21486-59-9(Hazardous Substances Data)

Upstream product

• 6579-27-7 2,6-dichlorobenzohydroximoyl chloride 
• 21486-28-2 4-Cyano-3-(2,6-dichlorophenyl)-5-methylisoxazole 

Relevant articles and documents

Electrochemical and yeast-catalysed ring-opening of isoxazoles in the synthesis of analogues of the herbicide Grasp

Isoxazoles substituted with an electron-withdrawing group at the 4-position undergo electrochemical and yeast-catalysed N-O bond cleavage. The electrolysis is much more efficient and, with acyl- and alkoxycarbonyl-substituted isoxazoles, it affords the enolised dicarbonylimine functionality characteristic of the herbicide Grasp. Regioisomeric 4- and 5-substituted isoxazoles are accessible through nitrile oxide cycloaddition chemistry, using halogen as a steric auxiliary to control the regiochemistry of reaction. Crystal data for compounds 11 and 19b are presented.