215033-86-6

Basic information

• Product Name: TiCl2(α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolate)(1,2-bis(diphenylphosphino)ethane)
• CAS NO: 215033-86-6
• Molecular Weight: 981.771
• Mol File: 215033-86-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: TiCl2(α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolate)(1,2-bis(diphenylphosphino)ethane)(CAS DataBase Reference)
• NIST Chemistry Reference: TiCl2(α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolate)(1,2-bis(diphenylphosphino)ethane)(215033-86-6)
• EPA Substance Registry System: TiCl2(α,α,α',α'-tetraphenyl-1,3-dioxolane-4,5-dimethanolate)(1,2-bis(diphenylphosphino)ethane)(215033-86-6)

Safety Data

• Hazardous Substances Data: 215033-86-6(Hazardous Substances Data)

Upstream product

• 93222-42-5 (4RS,5RS)-2,2-dimethyl-α,α,α′,α′-tetraphenyl-1,3-dioxolane-4,5-dimethanol 
• 7550-45-0 titanium tetrachloride 
• 1663-45-2 1,2-bis-(diphenylphosphino)ethane 

Relevant articles and documents

Facile syntheses of TiCl2(TADDOLate)(L2), efficient asymmetric ethylation of PhCHO, and an unexpected rearrangement of the tetramethyl analogue of the TADDOL ligand

Facile syntheses of TiCl2(TADDOLate)L2 (TADDOL = α,α,α′,α′-tetraphenyl-l,3-dioxolane-4,5- dimethanol; L = THF (1), AcOEt (2)) were developed from reactions of TiCl4 with the TADDOL ligand in coordinating solvent L. The labile solvent ligands L can be replaced by a neutral bidentate ligand such as 1,2-bis(diphenylphosphino)ethane (dppe) or 3,3-dimethyl-2,4-pentanedione (diketone) to give TiCl2(TADDOLate)(L2) (L2 = dppe (3), diketone (4)). The molecular structure of complex 3 shows a structure with two chlorides in trans positions, and the dppe ligand is trans to the strong alkoxide ligands. The most significant features of the structure are the long Ti-P(phosphine) bond distances observed, indicating considerable steric hindrance arising from the TADDOLate ligand in the complex. In a reaction of the TADDOL analogue α,α,α′,α′-tetramethyl-1,3-dioxolane-4,5- dimethanol with TiCl4 in Et2O, the unexpected complex 6 derived from rearrangement of the chiral diol ligand was obtained. This rearrangement is apparently mediated by TiCl4 with the conversion of the 2,3-ketal-1,4-diol into the isomeric 3,4-ketal-1,2-diol. The asymmetric ethylations of benzaldehyde catalyzed by the complex 1, 2, or 3/Ti(O-J-Pr)4 system are efficient, and the enantioselectivities are good, with values of enantiomeric excess up to 89%.