21511-90-0

Basic information

• Product Name: N-(1,2-diphenylethyl)acetamide
• CAS NO: 21511-90-0
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.3123
• Mol File: 21511-90-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 424.7°C at 760 mmHg
• Flash Point: 257.3°C
• Density: 1.074g/cm³
• Vapor Pressure: 2.03E-07mmHg at 25°C
• Refractive Index: 1.571
• CAS DataBase Reference: N-(1,2-diphenylethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,2-diphenylethyl)acetamide(21511-90-0)
• EPA Substance Registry System: N-(1,2-diphenylethyl)acetamide(21511-90-0)

Safety Data

• Hazardous Substances Data: 21511-90-0(Hazardous Substances Data)

Upstream product

• 14224-99-8 2-methyl-4,5-diphenyloxazole 
• 25611-78-3 (R,S)-1,2-diphenylethylamine 
• 108-24-7 acetic anhydride 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 75-36-5 acetyl chloride 
• 5773-56-8 1,2-Diphenylethanol 
• 75-05-8 acetonitrile 
• 6335-83-7 4-(2-phenylethyl)phenol 
• 3839-46-1 stilben-4-ol 
• 14310-21-5 1-(4-methoxyphenyl)-2-phenylethane 
• 100-52-7 benzaldehyde 
• 108-88-3 toluene 
• 100-42-5 styrene 
• 369-57-3 benzenediazonium tetrafluoroborate 

Downstream Products

• 77988-84-2 N-(1,2-diphenethyl)acetimidoyl chloride 
• 135365-09-2 cis-6,10b-dihydro-10b-methyl-5-phenyl-5H-oxazolo<2,3-a>isoquinoline-2,3-dione 
• 135365-21-8 1-methyl-3-phenyl-3,4-dihydroisoquinoline 

Relevant articles and documents

Metal-Organic Layers Catalyze Photoreactions without Pore Size and Diffusion Limitations

Metal-organic frameworks (MOFs) have emerged as promising single-site solid catalysts for organic reactions. However, MOF catalysts suffer from pore size limitation and slow diffusion, which are detrimental for photoreactions. Metal-organic layers (MOLs)

The photoredox-catalyzed meerwein addition reaction: Intermolecular amino-arylation of alkenes

A variety of amides are efficiently accessible under mild conditions by intermolecular amino-arylation using a photo Meerwein addition with visible light. The reaction has a broad substrate scope, tolerates a large range of functional groups, and was applied to the synthesis of a 3-aryl-3,4- dihydroisoquinoline. From elimination to addition: A variety of amides are efficiently accessible under mild conditions by intermolecular amino-arylation using a photo Meerwein addition with visible light. The reaction has a broad substrate scope, tolerates a large range of functional groups, and was applied to the synthesis of 3-aryl-3,4-dihydroisoquinoline. Copyright

A Modified Bischler-Napieralski Procedure for the Synthesis of 3-Aryl-3,4-dihydroisoquinolines

A modification of the Bischler-Napieralski reaction for the cyclization of (1,2-diphenylethyl)amides to the 3-aryl-3,4-dihydroisoquinolines is presented.Elimination of the amide group as the nitrile via the retro-Ritter reaction is avoided by its conversion to an N-acyliminium intermediate with oxalyl chloride-FeCl3.Removal of the oxalyl group in refluxing MeOH-sulfuric acid provides the 3,4-dihydroisoquinolines in moderate to high yields.The method is also highly effective with (2-phenylethyl)amides.