215317-22-9

Basic information

• Product Name: (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one
• Synonyms: (6R)-5,6-Dihydro-4-hydroxy-3-[(1R)-1-(3-nitrophenyl)propyl]-6-(2-phenylethyl)-6-propyl-2H-pyran-2-one
• CAS NO: 215317-22-9
• Molecular Formula: C₂₅H₂₉NO₅
• Molecular Weight: 423.5
• Mol File: 215317-22-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 587.2°C at 760 mmHg
• Flash Point: 308.9°C
• Density: 1.193g/cm³
• Vapor Pressure: 1.25E-14mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one(215317-22-9)
• EPA Substance Registry System: (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one(215317-22-9)

Safety Data

• Hazardous Substances Data: 215317-22-9(Hazardous Substances Data)

Usage

Description

(2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one is a complex organic compound characterized by a 3H-pyran ring with a hydroxyl group and a nitro group attached to different carbon atoms. It features a phenethyl and propyl group, along with a 2-phenethyl-2-propyl side chain. The stereochemistry of this compound is defined by the (2R) and (1R) configurations, which describe the arrangement of substituents around the chiral centers. This unique molecular structure may offer potential applications in various fields, such as pharmaceuticals and materials science, although further research is required to explore its properties and uses.

Uses

Used in Pharmaceutical Industry:
(2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one is used as a potential pharmaceutical compound for its unique molecular structure and stereochemistry. The presence of hydroxyl and nitro groups, along with the phenethyl and propyl groups, may contribute to its biological activity and interactions with biological targets, making it a candidate for drug development.
Used in Materials Science:
In the field of materials science, (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one may be utilized for its structural properties and potential to form novel materials with specific characteristics. (2R)-4-hydroxy-5-[(1R)-1-(3-nitrophenyl)propyl]-2-phenethyl-2-propyl-3H-pyran-6-one's chiral centers and side chains could influence its self-assembly, aggregation, or interaction with other molecules, leading to applications in areas such as nanotechnology, polymer science, or advanced materials development.

Upstream product

• 215317-20-7 (R)-5-Hydroxy-2-[(S)-1-(3-nitro-phenyl)-propyl]-3-oxo-5-phenethyl-octanoic acid methyl ester 
• 215317-11-6 (R)-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanol 
• 215317-14-9 (R)-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanal 
• 215317-08-1 (R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate 
• 215317-17-2 (R)-5-(Biphenyl-4-yloxymethoxy)-3-hydroxy-2-[(S)-1-(3-nitro-phenyl)-propyl]-5-phenethyl-octanoic acid methyl ester 
• 215317-19-4 (R)-5-(Biphenyl-4-yloxymethoxy)-2-[(S)-1-(3-nitro-phenyl)-propyl]-3-oxo-5-phenethyl-octanoic acid methyl ester 
• 215316-59-9 (R)-3-hydroxy-3-(2-phenylethyl)-hexanoic acid 

Downstream Products

• 174485-90-6 (R)-3-[(R)-1-(3-Amino-phenyl)-propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-pyran-2-one 
• 174484-41-4 tipranavir 
• 1141510-05-5 (6R)-4-hydroxy-3-[(R)-1-(3-hydroxyaminophenyl)-1-propyl]-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one 

Relevant articles and documents

2,5-Dimethyl-3,4-bis[(2R,5R)-2,5-dimethylphospholano]thiophene: First member of the hetero-DuPHOS family

The 2,5-dimethyl-3,4-bis[(2R,5R)-2,5-dimethylphospholano]thiophene (UlluPHOS), a new thiophene-based analogue of (R,R)-1,2-bis(phospholano)benzene (Me-DuPHOS), was synthesized, geometrically and electronically characterized, and employed as ligand of Rh and Ru in some standard hydrogenation reactions of prostereogenic functionalized carbon-carbon and carbon-oxygen double bonds. The synthesis of UlluPHOS is much easier than that provided for Me-DuPHOS. UlluPHOS and Me-DuPHOS display very similar geometries, while the electronic availability of the former is higher than that exhibited by the latter. The Rh and Ru complexes of UlluPHOS produced excellent enantiomeric excesses (98.9-99.5%) in the hydrogenation of N-acetyl-α-enamino acids and reaction rates higher than those found when employing the analogous complexes of Me-DuPHOS.