215319-12-3Relevant articles and documents
Design, synthesis and antibacterial activity of novel N-formylhydroxylamine derivatives as PDF inhibitors
Yin,Jia,Zhao,Xu,Tang,Wang
, p. 695 - 703 (2011/07/29)
A new series of N-formylhydroxylamines 11a-i have been synthesized through a multi-step protocol starting from diethyl malonate. These compounds have been structurally characterized by IR, 1H NMR and HRMS. All the synthesized compounds 11a-i have been screened for antibacterial activities. All the compounds are found to exhibit potent in vitro inhibitory activity against Staphylococcus aureus and relatively weak antibacterial activity against Klebsiella pneumoniae.
AZABICYCLONONENE DERIVATIVES AS RENIN INHIBITORS
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Page/Page column 32, (2010/11/08)
The invention relates to novel bicyclononene derivatives, related compounds and use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the