215530-62-4

Basic information

• Product Name: 6-CHLORO-[1,2,4]TRIAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID
• Synonyms: 6-CHLORO-[1,2,4]TRIAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID;4]triazolo[1;5-b]pyridazine-2-carboxylic acid;6-chloro-[1
• CAS NO: 215530-62-4
• Molecular Formula: C₆H₃ClN₄O₂
• Molecular Weight: 198.57
• Product Categories: CHIRAL CHEMICALS
• Mol File: 215530-62-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.967 g/cm³
• Refractive Index: 1.835
• PKA: -4.65±0.41(Predicted)
• CAS DataBase Reference: 6-CHLORO-[1,2,4]TRIAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-[1,2,4]TRIAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID(215530-62-4)
• EPA Substance Registry System: 6-CHLORO-[1,2,4]TRIAZOLO[1,5-B]PYRIDAZINE-2-CARBOXYLIC ACID(215530-62-4)

Safety Data

• Hazardous Substances Data: 215530-62-4(Hazardous Substances Data)

Usage

General Description

6-Chloro-[1,2,4]triazolo[1,5-b]pyridazine-2-carboxylic Acid is a synthetic organic compound, which belongs to the class of chemicals known as triazolopyridazines. Characterized by a triazolopyridazine skeletal structure, it is comprised of a pyridazine ring fused to a triazole ring. It contains a carboxylic acid group (COOH) and a chloride atom at the 6th position of the pyridazine ring. The precise properties of this chemical, such as its physical state, melting point, boiling point, or potential uses, are not widely documented, which usually suggests it is of particular interest within academic or industrial research contexts. Like all chemicals, handling and usage of this compound should observe standard safety procedures including appropriate personal protective equipment and adherence to local regulations.

InChI:InChI=1/C6H3ClN4O2/c7-3-1-2-4-8-5(6(12)13)10-11(4)9-3/h1-2H,(H,12,13)

Upstream product

• 55643-82-8 6-Chloro-2-methyl-s-triazolo<1,5-b>pyridazine 

Downstream Products

• 215530-36-2 [6-[3-[4-(diphenylmethoxy)piperidino]-propylamino][1,2,4]triazolo[1,5-b]pyridazin-2-yl]carboxylic acid 
• 215530-43-1 [6-[3-[4-(diphenylmethoxy)piperidino]-propoxy][1,2,4]triazolo[1,5-b]pyridazin-2-yl]carboxylic acid 
• 215530-42-0 isopropyl [6-[3-[4-(diphenylmethoxy)-piperidino]propoxy][1,2,4]triazolo[1,5-b]pyridazin-2-yl]carboxylate 

Relevant articles and documents

Condensed pyridazine derivatives, their production and use

A condensed pyridazine derivative which is useful as a pharmaceutical composition for preventing or treating allergic skin diseases such as contact dermatitis, pruritus, dried dermatitis, acute urticaria and prurigo.

NASAL DROPS CONTAINING FUSED PYRIDAZINE DERIVATIVES

A nose drop containing the compound (I) represented by the formula wherein Ar1 and Ar2 are each an aromatic group, Ar1 and Ar2 optionally form a condensed cyclic group together with the adjacent carbon atom, ring B is a nitrogen-containing heterocycle, X and Y are each a bond, an oxygen atom or S(O)p (p is 0 to 2), NR4 (R4 is H or a lower alkyl group) or a divalent linear lower hydrocarbon group optionally having substituents and containing 1 to 3 heteroatoms, A is N or CR7 (R7 is H, a halogen atom, a hydrocarbon group, an acyl group or a hydroxy group optionally having substituents), R1, R2 and R3 are each H, a halogen atom, a hydrocarbon group, an acyl group or a hydroxy group optionally having substituents, and R8 is H, a hydroxy group optionally substituted by a lower alkyl group or a carboxyl group, provided that the nitrogen-containing heterocycle represented by ring B is not a heterocycle represented by the formula wherein n is 0 - 1, or a salt thereof or a prodrug thereof, exhibits a superior prophylactic or therapeutic effect on allergic rhinitis and the like.