215608-40-5

Basic information

• Product Name: methyl (2R,4R)-4-<(benzyloxycarbonyl)amino>-2-hydroxy-5-methylhexanoate
• Synonyms: methyl (2R,4R)-4-<(benzyloxycarbonyl)amino>-2-hydroxy-5-methylhexanoate
• CAS NO: 215608-40-5
• Molecular Weight: 309.362
• Mol File: 215608-40-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (2R,4R)-4-<(benzyloxycarbonyl)amino>-2-hydroxy-5-methylhexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R,4R)-4-<(benzyloxycarbonyl)amino>-2-hydroxy-5-methylhexanoate(215608-40-5)
• EPA Substance Registry System: methyl (2R,4R)-4-<(benzyloxycarbonyl)amino>-2-hydroxy-5-methylhexanoate(215608-40-5)

Safety Data

• Hazardous Substances Data: 215608-40-5(Hazardous Substances Data)

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 5699-54-7 (R)-3-amino-4-methylpentanoic acid 
• 72-18-4 L-valine 
• 215608-34-7 methyl (R)-4-<(benzyloxycarbonyl)amino>-5-methyl-2-oxohexanoate 
• 215608-32-5 (R)-3-<(benzyoxycarbonyl)amino>-4-methylpentanoic acid 
• 172695-23-7 (R)-3-<(tert-butoxycarbonyl)amino>-4-methylpentanenitrile 
• 122818-28-4 (S)-2-(N-tert-butoxycarbonylamino)-3-methylbutyl tosylate 
• 501-53-1 benzyl chloroformate 
• 796039-35-5 (4S)-4-benzyloxycarbonylamino-5-methylhex-2-enoic acid methyl ester 
• 138754-84-4 N-benzyloxycarbonyl-L-valinal 
• 6216-65-5 N-benzyloxycarbonyl-L-valinol 
• 796039-36-6 (4R)-4-benzyloxycarbonylamino-5-methylhexanoic acid methyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 796039-37-7 (2R,4R)-4-benzyloxycarbonylamino-2-(tert-butyldiphenylsilanyloxy)-5-methylhexanoic acid methyl ester 
• 796039-44-6 (1'R,2'R)-[1-(2-carbamoyl-2-hydroxyethyl)-2-methylpropyl]carbamic acid benzyl ester 
• 796039-50-4 (1R,2'R,1'''R,3'''S)-{1-[2'-{4''-[1'''-benzyl-4'''-(tert-butyldiphenylsilanyloxy)-3'''-methylbutylcarbamoyl]thiazol-2''-yl}-2'-(tert-butyldiphenylsilanyloxy)ethyl]-2-methylpropyl}carbamic acid benzyl ester 
• 796039-49-1 (1R,2'R,1'''R,3'''S)-{1-[2'-{4''-[1'''-benzyl-4'''-(tert-butyldiphenylsilanyloxy)-3'''-methylbutylcarbamoyl]oxazol-2''-yl}-2'-(tert-butyldiphenylsilanyloxy)ethyl]-2-methylpropyl}carbamic acid benzyl ester 
• 796039-52-6 (1R,2'R,1''R,3''S)-acetic acid 1-{4'-[1''-benzyl-4''-(tert-butyldiphenylsilanyloxy)-3''-methylbutylcarbamoyl]thiazol-2'-yl}-3-benzyloxycarbonylamino-4-methylpentyl ester 
• 796039-51-5 (1R,2'R,1'''R,3'''S)-[1-(2'-{4''-[1'''-benzyl-4'''-(tert-butyldiphenylsilanyloxy)-3'''-methylbutylcarbamoyl]thiazol-2''-yl}-2'-hydroxyethyl)-2-methylpropyl]carbamic acid benzyl ester 
• 796039-41-3 (2S,2'R,4'R)-2-[4'-benzyloxycarbonylamino-2'-(tert-butyldiphenylsilanyloxy)-5'-methylhexanethioylamino]-3-hydroxypropionic acid methyl ester 
• 796039-38-8 (2S,2'R,4'R)-2-[4'-benzyloxycarbonylamino-2'-(tert-butyldiphenylsilanyloxy)-5'-methylhexanoylamino]-3-hydroxypropionic acid methyl ester 
• 796039-55-9 (1R,3R,1''R,3''S)-acetic acid 1-[4'-(1''-benzyl-4''-hydroxy-3''-methylbutylcarbamoyl)thiazol-2'-yl]-3-benzyloxycarbonylamino-4-methylpentyl ester 
• 796039-60-6 (1'R,3'R)-2-[3'-benzyloxycarbonylamino-1'-(tert-butyldiphenylsilanyloxy)-4'-methylpentyl]thiazole-4-carboxylic acid ethyl ester 
• 851124-19-1 2-[(1R,3R)-3-Benzyloxycarbonylamino-1-(tert-butyl-diphenyl-silanyloxy)-4-methyl-pentyl]-thiazole-4-carboxylic acid 
• 796039-39-9 (4S,1'R,3'R)-2-[3'-benzyloxycarbonylamino-1'-(tert-butyldiphenylsilanyloxy)-4'-methylpentyl]-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 851119-05-6 2-[(1R,3R)-3-Benzyloxycarbonylamino-1-(tert-butyl-diphenyl-silanyloxy)-4-methyl-pentyl]-oxazole-4-carboxylic acid 
• 796039-42-4 (4S,1'R,3'R)-2-[3'-benzyloxycarbonylamino-1'-(tert-butyldiphenylsilanyloxy)-4'-methylpentyl]-4,5-dihydrothiazole-4-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis of the tubuvaline-tubuphenylalanine (Tuv-Tup) fragment of tubulysin

(Chemical Equation Presented) Advanced intermediates and analogues of tubulysins were prepared in a convergent strategy.