215653-83-1

Basic information

• Product Name: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-[1,2,4]triazole-3-carboxylic acid amide
• CAS NO: 215653-83-1
• Molecular Weight: 530.58
• Mol File: 215653-83-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-[1,2,4]triazole-3-carboxylic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-[1,2,4]triazole-3-carboxylic acid amide(215653-83-1)
• EPA Substance Registry System: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-[1,2,4]triazole-3-carboxylic acid amide(215653-83-1)

Safety Data

• Hazardous Substances Data: 215653-83-1(Hazardous Substances Data)

Upstream product

• 36791-04-5 ribavirin 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 40372-06-3 1-(2'-deoxy-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide 

Relevant articles and documents

Imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide deoxynucleotides as simplified DNA building blocks with ambiguous pairing capacity

2'-Deoxynucleosides of imidazole-4 (or 1,2,4-triazole-3)-carboxamide, ethyl imidazole-4 (or 1,2,4-triazole-3)-carboxylate were synthesized by enzymatic glycosylation using N-deoxyribosyltransferase from a lactobacterium. The base pairing properties of Y and V when placed opposite the natural DNA bases as well as their serf were evaluated by thermal denaturation experiments. DNA templates containing imidazole-4-carboxamide base were used in elongation reaction catalysed by Klenow fragment.