21581-49-7

Basic information

• Product Name: 1,2-Benzenediol, 4-(2-aminoethyl)-5-nitro-
• CAS NO: 21581-49-7
• Molecular Formula: C8H10N2O4
• Molecular Weight: 198.178
• Mol File: 21581-49-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenediol, 4-(2-aminoethyl)-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenediol, 4-(2-aminoethyl)-5-nitro-(21581-49-7)
• EPA Substance Registry System: 1,2-Benzenediol, 4-(2-aminoethyl)-5-nitro-(21581-49-7)

Safety Data

• Hazardous Substances Data: 21581-49-7(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

This is an alternative name for the compound, which is derived from its structure and functional groups.

Explanation

The compound is a derivative of catechol, which is a 1,2-benzenediol, with modifications at the 4th position.

Explanation

The compound contains an aromatic ring (benzene), two hydroxyl groups, an amino group, and a nitro group, which contribute to its chemical properties.

Explanation

The compound is used in various research areas, including coordination chemistry, material science, and pharmaceuticals.

Explanation

The compound has been studied for its potential benefits in the fields of biology and medicine, particularly as an antioxidant and antimicrobial agent.

Explanation

Due to the presence of hydroxyl and amino groups, the compound is expected to be soluble in polar solvents.

Explanation

The presence of the nitro group and the amino group in the compound may make it sensitive to various environmental factors, such as light, heat, and pH changes.

Explanation

As a chemical compound, it is important to handle it with care due to its potential hazards, including irritation, toxicity, and harmful effects upon inhalation or skin absorption.

Explanation

Proper storage conditions are essential to maintain the stability and safety of the compound, preventing degradation or hazardous reactions.

Structure

1,2-Benzenediol with a nitro group and an aminoethyl substituent at the 4th position

Functional groups

Aromatic ring, hydroxyl groups, amino group, and nitro group

Applications

Research as a ligand for metal ions, synthesis of coordination polymers, and investigation for biological and pharmaceutical properties

Biological and pharmaceutical properties

Antioxidant and antimicrobial activities

Solubility

Soluble in polar solvents such as water and alcohols

Stability

May be sensitive to light, heat, and acidic or basic conditions

Hazards

Potential irritant, toxic by ingestion, and harmful if inhaled or absorbed through the skin

Storage

Store in a cool, dry, and well-ventilated area, away from heat, light, and incompatible substances

Upstream product

• 51-61-6 dopamine 
• 62-31-7 dopamine hydrochloride 

Downstream Products

• 868962-05-4 (dppe)Pd(5-nitrodopamine^(2-)) 

Relevant articles and documents

Bioinspired underwater bonding and debonding on demand

Mussel glue: Bioinspired underwater chemical bonding with the possibility of phototriggered debonding is reported. A four-arm star-poly(ethyleneglycol) end-functionalized by nitrodopamine was synthesized. The nitrodopamine offered the reactivity of catech

Erratum: Linking molecular behavior to macroscopic properties in ideal dynamic covalent networks (Journal of the American Chemical Society (2020) 142: 36 (15371-15385) DOI: 10.1021/jacs.0c06192)

The "concentration of functional groups, c,"was defined incorrectly on page S18 of the Supporting Information. The (Table Presented) correct definition is as follows: c is the concentration of functional groups of one of the two network components, assuming that both components are present in equal amounts. Therefore, in a network formed from tetrafunctional macromers (f = 4) and where the total molar concentration of macromers is [PEG], c = f [PEG]/2 = 4[PEG]/2 = 2[PEG]. In the original Supporting Information, we took c as the total concentration of functional groups in the network, resulting in c = 4[PEG]. This formula was incorrect and resulted in erroneous values for select Keq or Gp data reported in Table 1 (page 15374) and Figure 8 (page 15381). The corrected Table 1 and Figure 8 are shown below, and the SI has been corrected accordingly. In addition, some of these data that are quoted in the article should be changed as follows (with the corrected values highlighted in bold). On page 15374: "Keq,c = 37.5 when c = 0.02 M,""Keq was determined to be 540 ± 65. [?] corresponding to Gp = 10.9 ± 2.0 kPa,"and "Keq was quantified as 277 ± 37 from NMR and 323 from DFT, corresponding to Gp = 8.0 ± 0.8 and 9.0 kPa, respectively."On page 15381: "The rheometric data exhibited a similar increase in Keq from 75 at pH 6 to 10750 at pH 9 (Figure 8c)"and "At pH 9, Keq = 1126 ± 108 and 565 (from spectroscopy and rheology, respectively) and then decreased sharply at pH 10 to Keq = 112 and 120 (Figure 8e,f)."On page 15373 (in the Figure 2 caption): "Keq = 540 ± 65."'Table Presented' These corrections do not affect any of the conclusions of the article but only the exact value of select parameters. We apologize for these errors and for any inconvenience caused to the readers. ? Associated Content: ? Supporting Information The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/jacs.0c10406. Synthesis, sample preparation, computational and experimental methods, and model descriptions (PDF). (Figure Presented).

METAL NANOPARTICLE SURFACE LIGAND REPLACEMENT METHOD

The invention relates to a method of producing inorganic nanoparticles with a polar surface, a) providing an inorganic nanoparticle with a coordinated organic ligand to the nanoparticles surface, b) providing a replacement salt comprising a replacement io