215815-08-0

Basic information

• Product Name: 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE
• Synonyms: 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE
• CAS NO: 215815-08-0
• Molecular Formula: C₁₀H₁₁BrO₄S
• Molecular Weight: 307.16
• Mol File: 215815-08-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 435.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.545±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE(215815-08-0)
• EPA Substance Registry System: 5-BROMO-2-PROPIONYLPHENYL METHANESULFONATE(215815-08-0)

Safety Data

• Hazardous Substances Data: 215815-08-0(Hazardous Substances Data)

Upstream product

• 17764-92-0 1-(4-bromo-2-hydroxyphenyl)-propan-1-one 
• 124-63-0 methanesulfonyl chloride 
• 591-20-8 3-Bromophenol 

Downstream Products

• 199172-08-2 6-bromo-1-cyclohexyl-3-ethyl-1H-indazole 
• 215815-09-1 6-bromo-1-methyl-3-ethyl-1H-indazole 

Relevant articles and documents

ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS

The present invention provides a compound of formula (I):said compound is inhibitor of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP-13, and thus can be employed for the treatment of a disorder or disease characterized by abnormal activity of MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12 and/or MMP- 13. Accordingly, the compound of formula (I) can be used in treatment of disorders or diseases mediated by MMP-2, and/or MMP-8, and/or MMP-9, and/or MMP-12, and/or MMP- 13. Finally, the present invention also provides a pharmaceutical composition.

Processes and intermediates for preparing substituted indazole derivatives

PCT No. PCT/IB98/00647 Sec. 371 Date May 27, 1999 Sec. 102(e) Date May 27, 1999 PCT Filed Apr. 28, 1998 PCT Pub. No. WO98/50367 PCT Pub. Date Nov. 12, 1998The invention relates to processes and intermediates for preparing compounds of formula (I) and phar