215867-18-8Relevant articles and documents
Synthesis and pharmacological characterization of 4-substituted-2- aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: Identification of new potent and selective metabotropic glutamate 2/3 receptor agonists
Monn, James A.,Valli, Matthew J.,Massey, Steven M.,Hao, Junliang,Reinhard, Matthew R.,Bures, Mark G.,Heinz, Beverly A.,Wang, Xushan,Carter, Joan H.,Getman, Brian G.,Stephenson, Gregory A.,Herin, Marc,Catlow, John T.,Swanson, Steven,Johnson, Bryan G.,McKinzie, David L.,Henry, Steven S.
, p. 4442 - 4455 (2013/07/19)
As part of our ongoing interest in identifying novel agonists acting at metabotropic glutamate (mGlu) 2/3 receptors, we have explored the effect of structural modifications of 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6- dicarboxylate (LY354740), a potent