2159-38-8

Basic information

• Product Name: 2-(3-nitrobenzoyl)benzoic acid
• Synonyms: 2-(3-Nitrobenzoyl)benzoic acid; benzoic acid, 2-(3-nitrobenzoyl)-
• CAS NO: 2159-38-8
• Molecular Formula: C₁₄H₉NO₅
• Molecular Weight: 271.225
• Mol File: 2159-38-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 517.4°C at 760 mmHg
• Flash Point: 220.5°C
• Density: 1.413g/cm³
• Vapor Pressure: 1.56E-11mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 2-(3-nitrobenzoyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-nitrobenzoyl)benzoic acid(2159-38-8)
• EPA Substance Registry System: 2-(3-nitrobenzoyl)benzoic acid(2159-38-8)

Safety Data

• Hazardous Substances Data: 2159-38-8(Hazardous Substances Data)

Usage

Structure

A benzene ring with a nitro group attached to the third position and a benzoyl group attached to the second position.

Derivative

Benzoic acid

Usage

Organic synthesis, building block for pharmaceuticals and materials, production of dyes, pigments, and other organic compounds

Hazardous nature

Considered a hazardous substance, requires careful handling and disposal

Upstream product

• 85-52-9 2-Benzoylbenzoic acid 
• 20643-69-0 3-(m-nitrophenyl)-3-methoxyphthalide 
• 7697-37-2 nitric acid 
• 7664-93-9 sulfuric acid 
• 85-44-9 phthalic anhydride 
• 98-95-3 nitrobenzene 

Downstream Products

• 32017-74-6 2-(3-nitro-benzoyl)-benzoic acid methyl ester 
• 82-34-8 1-nitroanthraquinone 
• 605-27-6 2-nitroanthraquinone 
• 13450-37-8 o-(3-chloro-benzoyl)-benzoic acid 
• 6268-18-4 2-(3-amino-benzoyl)-benzoic acid 
• 16063-03-9 2-(3-nitrophenyl)-4H-3,1-benzoxazin-4-one 
• 854166-16-8 2-(3-nitro-benzoyl)-benzoyl azide 
• 149816-87-5 9b-(3-nitrophenyl)-2,3-dihydrothiazolo<2,3-a>isoindol-5(9bH)-one 
• 632340-55-7 2-(3'-nitrobenzyl)benzoic acid 
• 632340-69-3 2-[3'-nitro(bromobenzyl)]benzoic acid 
• 149816-86-4 9b-(3-aminophenyl)-2,3-dihydrothiazolo<2,3-a>isoindol-5(9bH)-one 
• 5497-16-5 9b-(3-hydroxyphenyl)-2,3-dihydrothiazolo<2,3-a>isoindol-5(9bH)-one 
• 3882-50-6 2-amino-3'-nitro-benzophenone 
• 634602-13-4 2-(3-hydroxy-benzoyl)-benzoic acid 

Relevant articles and documents

Hydrolysis of 3-(m-Nitrophenyl)-3-methoxyphthalide

The hydrolysis of 3-(m-nitrophenyl)-3-methoxyphthalide to o-(m-nitrobenzoyl)benzoic acid is general-base catalyzed in acetate buffers at pH 4-6.The rate expression is: kobsd= 1.60*10-6+6.38*10-4+>+2.08*10

An alternative method for the synthesis of γ-lactones by using cesium fluoride-celite/acetonitrile combination

A variety of 2-(1-bromoalkyl) benzoic acids 4 undergo intramolecular nucleophilic substitution reaction when treated with a CsF-Celite as solid base in acetonitrile under reflux condition to give the corresponding cyclized phthalides in moderate to very good yield. These 2-(1-bromoalkyl) benzoic acids 4 are formed by the α-bromination of 2-alkylbenzoic acids 3 using N-bromosuccinimide and a catalytic amount of α,α′ -azoisobutyronitrile in carbon tetrachloride under reflux.