21615-25-8

Basic information

• Product Name: 1,2-Benzenedicarboxamide, N,N'-dicyclohexyl-
• CAS NO: 21615-25-8
• Molecular Formula: C20H28N2O2
• Molecular Weight: 328.455
• Mol File: 21615-25-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedicarboxamide, N,N'-dicyclohexyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarboxamide, N,N'-dicyclohexyl-(21615-25-8)
• EPA Substance Registry System: 1,2-Benzenedicarboxamide, N,N'-dicyclohexyl-(21615-25-8)

Safety Data

• Hazardous Substances Data: 21615-25-8(Hazardous Substances Data)

Upstream product

• 84-66-2 Diethyl phthalate 
• 108-91-8 cyclohexylamine 
• 2133-65-5 N-cyclohexylphthalimide 
• 601-70-7 3,3-dichlorophthalide 
• 88-95-9 Phthaloyl dichloride 
• 80991-87-3 N-cyclohexylisophthalimide 
• 35197-64-9 2-bromo-4-(1,3-dioxoisoindolin-2-yl)butanoic acid 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant articles and documents

The reaction of phthalidylidene dichloride with primary amines. Synthesis and X-ray molecular structure of N-substituted phthalisoimides

An efficient method for the synthesis of N-substituted phthalisoimides, by reaction of phthalidylidene dichloride with primary amines, is described. The reactions with arylamines, arylenediamincs and alkylenediamines lead to the corresponding phthalisoimides or bisphthalisoimides in nearly quantitative yields. However, the reactions with alkylamines are not useful because of the relatively high nucleophilicity of alkylamines. Certain particular behaviours of arylamines, associated with the presence of specific ortho-substituents have been found. The reactions of arylamines bearing an o-hydroxymethyl group provide a convenient method for preparing 2-benzoxazinylbenzoic acids. The X-ray crystallographic structures of N-(2-methoxyphenyl)phthalisoimide 3a and 2-(4H-3.1-benzoxazin-2-yl)benzoic acid 15a have been determined.

ACYLATION OF PRIMARY AND SECONDARY AMINES WITH CARBOXYLIC ACIDS IN PRESENCE OF AROMATIC SULFOCHLORIDES AND TERTIARY AMINES

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