21615-74-7

Basic information

• Product Name: 1(3H)-Isobenzofuranone, 3-(4-methoxyphenyl)-
• CAS NO: 21615-74-7
• Molecular Formula: C15H12O3
• Molecular Weight: 240.258
• Mol File: 21615-74-7.mol
• Article Data: 47

Chemical Properties

• CAS DataBase Reference: 1(3H)-Isobenzofuranone, 3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-Isobenzofuranone, 3-(4-methoxyphenyl)-(21615-74-7)
• EPA Substance Registry System: 1(3H)-Isobenzofuranone, 3-(4-methoxyphenyl)-(21615-74-7)

Safety Data

• Hazardous Substances Data: 21615-74-7(Hazardous Substances Data)

Upstream product

• 100538-34-9 3-(4-hydroxy-phenyl)-3H-benzofuran-2-one 
• 74-88-4 methyl iodide 
• 100-66-3 methoxybenzene 
• 119-67-5 o-carboxybenzaldehyde 
• 6889-78-7 4'-(methoxy)-3-hydroxyflavone 
• 123-11-5 4-methoxy-benzaldehyde 
• 98-88-4 benzoyl chloride 
• 4122-56-9 methyl o-formylbenzoate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 85-44-9 phthalic anhydride 
• 93-98-1 N-phenyl benzoyl amide 
• 1128-86-5 1-benzoyl-2,2-dimethylhydrazine 

Downstream Products

• 116515-58-3 4-Hydroxy-9-(4-methoxy-phenyl)-naphtho[2,3-c]furan-1,3-dione 
• 127257-67-4 5,12-dihydro-5,6,11,12-tetrakis(4-methoxyphenyl)-5,12-naphthacenediol 
• 127279-36-1 5,12-dihydro-5-(3-methoxyphenyl)-6,11-bis(4-methoxyphenyl)-12-phenyl-5,12-naphthacenediol 
• 127257-70-9 12-hydroxy-12-(3-methoxyphenyl)-6,11-bis(4-methoxyphenyl)naphthacen-5(12H)-one 
• 127257-78-7 5-(3-methoxyphenyl)-6,11-bis(4-methoxyphenyl)-12-phenylnaphthacene 
• 127257-76-5 tetra-4-anisoylrubrene 
• 116515-61-8 4-Hydroxy-9-(4-methoxy-phenyl)-3H-naphtho[2,3-c]furan-1-one 
• 116515-59-4 4-Hydroxy-4-(4-methoxy-phenyl)-3-methyl-3,4-dihydro-2H-naphthalen-1-one 
• 92753-27-0 (9R,10R)-1-(tert-Butyl-dimethyl-silanyloxy)-8-(4-methoxy-phenyl)-11-oxa-tricyclo[6.2.1.0^2,7]undeca-2⁽⁷⁾,3,5-triene-9,10-dicarboxylic acid dimethyl ester 
• 92753-30-5 2,3-dicarbomethoxy-4-hydroxy-1-p-anisylnaphthalene 

Relevant articles and documents

Application of a new solid-phase resin: Benzamide ortho-lithiation and the synthesis of a phthalide library

The utility of new polytetrahydrofuran cross-linked polystyrene resins is demonstrated through the solid-phase synthesis of a phthalide library. The phthalides are synthesized via directed ortho-lithiation of resin bound benzamides and isolated via cyclat

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Direct and selective synthesis of 3-arylphthalides via nickel-catalyzed aryl addition/intramolecular esterification

Herein we report a nickel-catalyzed aryl addition/intramolecular esterification in a cascade fashion. Under the combination of commercially available nickel precursor and tridentate ligand, the one pot protocol offers a direct, simple and regioselective approach to access 3-aryl phthalide derivatives from two readily available substrates with good efficiency, broad scope as well as satisfactory functional group compatibility.

Transition-Metal-Free Synthesis of Polyfunctional Triarylmethanes and 1,1-Diarylalkanes by Sequential Cross-Coupling of Benzal Diacetates with Organozinc Reagents

A variety of functionalized triarylmethane and 1,1-diarylalkane derivatives were prepared via a transition-metal-free, one-pot and two-step procedure, involving the reaction of various benzal diacetates with organozinc reagents. A sequential cross-coupling is enabled by changing the solvent from THF to toluene, and a two-step SN1-type mechanism was proposed and evidenced by experimental studies. The synthetic utility of the method is further demonstrated by the synthesis of several biologically relevant molecules, such as an anti-tuberculosis agent, an anti-breast cancer agent, a precursor of a sphingosine-1-phosphate (S1P) receptor modulator, and a FLAP inhibitor.