216173-04-5

Basic information

• Product Name: S-(4-hydroxybenzyl) ethanethioate
• Synonyms: S-(4-hydroxybenzyl) ethanethioate
• CAS NO: 216173-04-5
• Molecular Weight: 182.243
• Mol File: 216173-04-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: S-(4-hydroxybenzyl) ethanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(4-hydroxybenzyl) ethanethioate(216173-04-5)
• EPA Substance Registry System: S-(4-hydroxybenzyl) ethanethioate(216173-04-5)

Safety Data

• Hazardous Substances Data: 216173-04-5(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 89639-61-2 p-methylthiolphenol 
• 507-09-5 thioacetic acid 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 507-09-5 tiolacetic acid 

Downstream Products

• 1032290-98-4 1-[4-(acetylthiomethyl)phenoxy]-α-D-lyxopyranoside triacetate 
• 1032290-99-5 1-[4-(acetylthiomethyl)phenoxy]-β-D-lyxopyranoside triacetate 
• 502-87-4 4-methylene-cyclohexa-2,5-dienone 

Relevant articles and documents

In Vivo Imaging of Senescent Vascular Cells in Atherosclerotic Mice Using a β-Galactosidase-Activatable Nanoprobe

Senescence-associated diseases have severely diminished the quality of life and health of patients. However, a sensitive assay of these diseases remains limited due to a lack of straightforward methods. Considering that senescence-associated β-galactosidase (SA-β-Gal) is overexpressed in senescent cells, the detection of SA-β-Gal in senescent cells and tissues might be a feasible strategy for the early diagnosis of SA diseases. In this study, a β-galactosidase-activatable nanoprobe BOD-L-βGal-NPs was developed for the imaging of senescent cells and vasculature in atherosclerotic mice via real-time monitoring of β-Gal. BOD-L-βGal-NPs was fabricated by encapsulating a newly designed NIR ratiometric probe BOD-L-βGal within a poly(lactic-co-glycolic) acid (PLGA) core. Nanoprobe BOD-L-βGal-NPs showed good accumulation in arteries, thus successfully visualizing senescent cells and vasculature in atherosclerotic mice by tail vein injection. Our findings indicated that nanoprobe BOD-L-βGal-NPs holds great potential for the early diagnosis and therapy of atherosclerosis and other aging-associated diseases.

Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry

Tuning affinities: Dynamic combinatorial chemistry has been employed to explore the effect of chemical modifications on the DNA G-quadruplex binding properties of anoxazole-based peptide macrocycle. Two dynamic libraries of molecules, containing cationic and carbohydrate motifs, respectively, were screened by using structurally diverse nucleic acid targets (see scheme; each colored shape represents a cation or carbohydrate). (Chemical Equation Presented).