21633-79-4

Basic information

• Product Name: diethyl n-butyrylMalonate
• Synonyms: diethyl n-butyrylMalonate
• CAS NO: 21633-79-4
• Molecular Formula: C₁₁H₁₈O₅
• Molecular Weight: 230.25762
• Mol File: 21633-79-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 249.5°C (estimate)
• Appearance: /
• Density: 1.0560
• Refractive Index: 1.4451 (estimate)
• CAS DataBase Reference: diethyl n-butyrylMalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl n-butyrylMalonate(21633-79-4)
• EPA Substance Registry System: diethyl n-butyrylMalonate(21633-79-4)

Safety Data

• Hazardous Substances Data: 21633-79-4(Hazardous Substances Data)

Upstream product

• 27761-57-5 2-((E)-But-2-enoyl)-malonic acid diethyl ester 
• 109572-65-8 BrMgCH(CO₂Et)2 
• 141-75-3 butyryl chloride 
• 105-53-3 diethyl malonate 

Downstream Products

• 685-88-1 fluoromalonic acid diethyl ester 
• 3249-68-1 ethyl butyroyl acetate 
• 1443120-88-4 ethyl 2-oxo-6-phenyl-4-propyl-1,2-dihydropyridine-3-carboxylate 
• 1443120-90-8 ethyl 6-(4-methoxyphenyl)-2-oxo-4-propyl-1,2-dihydropyridine-3-carboxylate 
• 1443120-91-9 ethyl 6-(4-bromophenyl)-2-oxo-4-propyl-1,2-dihydropyridine-3-carboxylate 
• 1443120-97-5 diethyl 2-(1-oxo-1-phenylhex-3-en-3-yl)malonate 
• 1443120-99-7 diethyl 2-(1-(4-methoxyphenyl)-1-oxohex-3-en-3-yl)malonate 
• 1443121-01-4 C₁₉H₂₃BrO₅ 

Relevant articles and documents

Synthesis of β-arylacyl / β-heteroarylacyl-β-alkylidene malonates and their application in substituted pyridone synthesis

A novel approach has been developed for the synthesis of β-arylacyl/β-heteroarylacyl-β-alkylidine malonates in moderate to good yields by the reaction of Stork aryl and heteroaryl enamine with β-chloroalkylidene malonates. The reaction involves conjugate

PYRAZOLO ’3,4-B! PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE TYPE 4 (PDE4) INHIBITORS

The invention provides a compound of formula (I) or a salt thereof: formula (I) wherein W is Ar, -CR4R5Ar or a group (y) or (y1), wherein Ar is (x) or (z): formulae (x), (z), (y), (y1) R1 is C1-4alkyl, C1-3