216453-74-6

Basic information

• Product Name: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione
• Synonyms: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione;11-Keto Budesonide;Budesonide IMpurity L (11-Keto Budesonide, Mixture of DiastereoMers);11-Keto Budesonide (Mixture of DiastereoMers);16α,17-[(1RS)-butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione
• CAS NO: 216453-74-6
• Molecular Formula: C25H32O6
• Molecular Weight: 428.51798
• Product Categories: Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 216453-74-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 601.7±55.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
• PKA: 12.83±0.10(Predicted)
• CAS DataBase Reference: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione(CAS DataBase Reference)
• NIST Chemistry Reference: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione(216453-74-6)
• EPA Substance Registry System: (16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione(216453-74-6)

Safety Data

• Hazardous Substances Data: 216453-74-6(Hazardous Substances Data)

Usage

Description

(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione is a complex organic compound belonging to the class of steroids. It is characterized by its unique molecular structure, which includes a butylidenebis(oxy) bridge between carbons 16 and 17, and a hydroxyl group at the 21st position. This molecule is derived from the pregnane family, which is known for its diverse biological activities and potential applications in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione is used as an intermediate in the synthesis of various steroidal drugs for the treatment of different medical conditions. Its unique structure may provide specific pharmacological properties that can be exploited for the development of novel therapeutic agents.
Used in Research and Development:
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione is also utilized in research and development for understanding the structure-activity relationships of steroidal molecules. It can serve as a valuable tool in the design and optimization of new drugs targeting various diseases and disorders.
Used in Impurity Profiling:
(16α)-16,17-[Butylidenebis(oxy)]-21-hydroxypregna-1,4-diene-3,11,20-trione may be used as an impurity in the manufacturing process of related steroidal drugs. Understanding and controlling the presence of such impurities is crucial for ensuring the safety, efficacy, and quality of the final pharmaceutical product.