216501-07-4Relevant articles and documents
Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model
Zeng, Qingping,Kwok, Yan,Kerwin, Sean M.,Mangold, Gina,Hurley, Laurence H.
, p. 4273 - 4278 (1998)
A new class of pyridobenzophenoxazine compounds has been developed as topoisomerase II inhibitors for anticancer chemotherapy. These compounds were designed based on a proposed model of a quinobenzoxazine self-assembly complex on DNA. They showed excellen