216502-71-5

Basic information

• Product Name: 3-{5-[(S)-2-tert-Butoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethyl]-2-methoxy-phenylcarbamoyl}-piperidine-1-carboxylic acid benzyl ester
• Synonyms: 3-{5-[(S)-2-tert-Butoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethyl]-2-methoxy-phenylcarbamoyl}-piperidine-1-carboxylic acid benzyl ester
• CAS NO: 216502-71-5
• Molecular Weight: 607.627
• Mol File: 216502-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{5-[(S)-2-tert-Butoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethyl]-2-methoxy-phenylcarbamoyl}-piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{5-[(S)-2-tert-Butoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethyl]-2-methoxy-phenylcarbamoyl}-piperidine-1-carboxylic acid benzyl ester(216502-71-5)
• EPA Substance Registry System: 3-{5-[(S)-2-tert-Butoxycarbonyl-2-(2,2,2-trifluoro-acetylamino)-ethyl]-2-methoxy-phenylcarbamoyl}-piperidine-1-carboxylic acid benzyl ester(216502-71-5)

Safety Data

• Hazardous Substances Data: 216502-71-5(Hazardous Substances Data)

Upstream product

• 216502-61-3 (S)-3-(4-Hydroxy-3-nitro-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid tert-butyl ester 
• 216502-63-5 (S)-3-(4-Methoxy-3-nitro-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid tert-butyl ester 
• 78190-11-1 1-benzyloxycarbonylpiperidine-3-carboxylic acid 
• 16874-12-7 Tyr(tBu) 
• 216502-94-2 1-[(benzyloxy)carbonyl]piperidine-3-carbonyl chloride 
• 216502-65-7 (S)-3-(3-Amino-4-methoxy-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid tert-butyl ester 

Relevant articles and documents

Synthesis and evaluation of RGD peptidomimetics aimed at surface bioderivatization of polymer substrates

Several RGD peptidomimetics have been prepared, in a convergent way, from the common ortho-amino-tyrosine template (O-substituted with an anchorage-arm or a methyl group, and αN-substituted with a fluorine tag for XPS analysis), and various ω-aminoacid derivatives. The most flexible compounds have shown a biological activity similar to that of the peptide reference (RGDS) in the platelet aggregation test. The compound 16a could be fitted (by modelisation) with DMP 728 and c(RGDfV), two cyclic peptides that are good ligands of integrins. The compound 16b has been covalently fixed on the surface of a poly(ethylene terephthalate) membrane used as support for mammalian cell cultivation. Copyright (C) 1998 Elsevier Science Ltd.