21651-84-3 Usage
Description
(1S,2S)-2-METHYLAMINO-CYCLOHEXANOL, also known as MACH, is a synthetic organic compound with a molecular formula of C7H15NO. It is an enantiomerically pure form of 2-methylamino-cyclohexanol, characterized by its specific spatial arrangement of atoms. This chiral auxiliary is instrumental in organic synthesis, particularly for the production of pharmaceuticals and agrochemicals, due to its ability to control the chirality of reactions and yield enantiomerically pure products. Furthermore, it has demonstrated potential as a building block for the preparation of biologically active compounds.
Uses
Used in Pharmaceutical Industry:
(1S,2S)-2-METHYLAMINO-CYCLOHEXANOL is used as a chiral auxiliary for the synthesis of pharmaceuticals, leveraging its precise stereochemistry to control the chirality of reactions and produce enantiomerically pure products. This ensures the desired biological activity and therapeutic efficacy of the resulting drugs.
Used in Agrochemical Industry:
In the agrochemical sector, (1S,2S)-2-METHYLAMINO-CYCLOHEXANOL serves as a chiral auxiliary in the synthesis of agrochemicals, contributing to the development of enantiomerically pure compounds with targeted biological activity, which is crucial for effective pest control and crop protection.
Used in the Preparation of Biologically Active Compounds:
(1S,2S)-2-METHYLAMINO-CYCLOHEXANOL is utilized as a building block in the preparation of biologically active compounds, capitalizing on its structural properties to create new molecules with potential applications in various fields, including medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 21651-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,6,5 and 1 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 21651-84:
(7*2)+(6*1)+(5*6)+(4*5)+(3*1)+(2*8)+(1*4)=93
93 % 10 = 3
So 21651-84-3 is a valid CAS Registry Number.
21651-84-3Relevant articles and documents
Method for synthesizing trans-cyclohexanedimethanamine
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Paragraph 0011; 0012; 0013; 0014; 0015; 0016; 0017; 0018, (2017/08/28)
The invention discloses a method for synthesizing trans-cyclohexanedimethanamine, comprising steps of reacting cyclohexene oxide and methylamine aqueous solution under the catalysis of boric acid, and then adding sulfuric acid, dewatering to form an ester, ring-closing under alkaline conditions, adding methylamine aqueous solution and boric acid for hermetic reaction, and distilling to obtain trans-cyclohexanedimethanamine. The synthetic process is simple to perform, provides facilitated isolation and purification and high yield and product purity, and is suitable for batch production.
HYDRONOPOL DERIVATIVES AS AGONISTS ON HUMAN ORL1 RECEPTORS
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Page/Page column 18, (2010/02/13)
The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.
Enzymatic resolution of (±)-2-(N(β)-t-butoxycarbonyl-N(α)- methylhydrazino)cycloalkanols
Forro, Eniko,Szakonyi, Zsolt,Fueloep, Ferenc
, p. 4619 - 4626 (2007/10/03)
Racemates of cis- and trans-2-(N(β)-t-butoxycarbonyl-N(α)- methylhydrazino)cyclopentanols and -cyclohexanols 1-4 were resolved through lipase PS- or Novozym 435-catalysed asymmetric acylation of the secondary OH group at the (R)-stereogenic centre. High e
