21652-57-3Relevant articles and documents
Syntheses and properties of fluorous quaternary phosphonium salts that bear four ponytails; new candidates for phase transfer catalysts and ionic liquids
Emnet, Charlotte,Weber, Kathleen M.,Vidal, Jose A.,Consorti, Crestina S.,Stuart, Alison M.,Gladysz
, p. 1625 - 1634 (2006)
The fluorous tertiary phosphine [Rf6-(CH2) 2]3P [Rfn = CF3(CF2) n-1] and excess PhCH2Br, CH3(CH 2)3OSO2CF3
Combining lipase-catalyzed enantiomer-selective acylation with fluorous phase labeling: A new method for the resolution of racemic alcohols
Hungerhoff, Benno,Sonnenschein, Helmut,Theil, Fritz
, p. 1781 - 1785 (2007/10/03)
Lipase-catalyzed acylation of racemic alcohols with a highly fluorinated acyl donor allows their kinetic resolution accompanied by the simultaneous enantiomer-selective fluorous phase labeling. Both the tagged and the untagged enantiomer can be separated without chromatography by a very efficient partition between a fluorous and an organic phase. The method has been successfully applied to the resolution of typically racemic secondary alcohols of low molecular weight. The fluorous label can be recovered quantitatively.