216576-74-8 Usage
Description
4-Hexenoic acid, 3-(aminomethyl)-5-methyl-, also known as 4,5-Dehydropregabalin, is an impurity of the anticonvulsant drug Pregabalin. It is a pale beige solid with chemical properties that distinguish it from the main compound. As an impurity, it is important to monitor and control its presence in the manufacturing process to ensure the purity and efficacy of Pregabalin.
Uses
There are no specific applications mentioned for 4-Hexenoic acid, 3-(aminomethyl)-5-methylin the provided materials. However, it is an impurity in the production of Pregabalin, an anticonvulsant medication used to treat various conditions such as epilepsy, neuropathic pain, and generalized anxiety disorder. The control and monitoring of this impurity are crucial to maintain the quality and effectiveness of Pregabalin.
Check Digit Verification of cas no
The CAS Registry Mumber 216576-74-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,5,7 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 216576-74:
(8*2)+(7*1)+(6*6)+(5*5)+(4*7)+(3*6)+(2*7)+(1*4)=148
148 % 10 = 8
So 216576-74-8 is a valid CAS Registry Number.
216576-74-8Relevant articles and documents
PREGABALIN -4-ELIMINATE, PREGABALIN 5-ELIMINATE, THEIR USE AS REFERENCE MARKER AND STANDARD, AND METHOD TO PRODUCE PREGABALIN CONTAINING LOW LEVELS THEREOF
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Page/Page column 19-21, (2009/05/30)
The present invention provides 3- (aminomethyl)-5-methylhex-4-enoic acid (Pregabalin- 4-eliminate or PRG-4E) and 3- (aminomethyl)-5-methylhex-5-enoic acid (Pregabalin-5-eliminate or PRG-5E), and their uses as reference markers and standards for determining the purity of Pregabalin. The invention also provides a method to produce Pregabalin containing low levels of these impurities.